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Evaluating candidate autoantigens in rheumatoid arthritis.

作者信息

Cope A P, Sønderstrup G

机构信息

Kennedy Institute of Rheumatology, Hammersmith, London, UK.

出版信息

Springer Semin Immunopathol. 1998;20(1-2):23-39. doi: 10.1007/BF00831997.

DOI:10.1007/BF00831997
PMID:9836367
Abstract
摘要

相似文献

1
Evaluating candidate autoantigens in rheumatoid arthritis.评估类风湿关节炎中的候选自身抗原。
Springer Semin Immunopathol. 1998;20(1-2):23-39. doi: 10.1007/BF00831997.
2
T cell responses to a human cartilage autoantigen in the context of rheumatoid arthritis-associated and nonassociated HLA-DR4 alleles.在类风湿性关节炎相关和非相关HLA - DR4等位基因背景下，T细胞对人软骨自身抗原的反应。
Arthritis Rheum. 1999 Jul;42(7):1497-507. doi: 10.1002/1529-0131(199907)42:7<1497::AID-ANR25>3.0.CO;2-#.
3
Identification of an altered peptide ligand based on the endogenously presented, rheumatoid arthritis-associated, human cartilage glycoprotein-39(263-275) epitope: an MHC anchor variant peptide for immune modulation.基于内源性呈现的、与类风湿性关节炎相关的人软骨糖蛋白-39（263-275）表位鉴定改变的肽配体：用于免疫调节的MHC锚定变体肽
Arthritis Res Ther. 2007;9(4):R71. doi: 10.1186/ar2269.
4
Aire is not essential for regulating neuroinflammatory disease in mice transgenic for human autoimmune-diseases associated MHC class II genes HLA-DR2b and HLA-DR4.Aire 对于调控携带与人类自身免疫性疾病相关 MHC Ⅱ类基因 HLA-DR2b 和 HLA-DR4 的转基因小鼠的神经炎症性疾病并非必需。
Cell Immunol. 2018 Sep;331:38-48. doi: 10.1016/j.cellimm.2018.05.003. Epub 2018 May 14.
5
Induction of arthritis in HLA-DR4-humanized and HLA-DQ8-humanized mice by human cartilage proteoglycan aggrecan but only in the presence of an appropriate (non-MHC) genetic background.人软骨蛋白聚糖聚集蛋白聚糖可在HLA-DR4人源化小鼠和HLA-DQ8人源化小鼠中诱导关节炎，但仅在合适的（非MHC）遗传背景存在时才会发生。
Arthritis Rheum. 2004 Jun;50(6):1984-95. doi: 10.1002/art.20285.
6
Identification of citrullinated vimentin peptides as T cell epitopes in HLA-DR4-positive patients with rheumatoid arthritis.在类风湿性关节炎的HLA - DR4阳性患者中鉴定瓜氨酸化波形蛋白肽作为T细胞表位。
Arthritis Rheum. 2010 Jan;62(1):117-25. doi: 10.1002/art.25059.
7
The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.HLA-DR4的共享易感性表位结合瓜氨酸化自身抗原和T细胞受体。
Sci Immunol. 2021 Apr 16;6(58). doi: 10.1126/sciimmunol.abe0896.
8
Differential MHC class II-mediated presentation of rheumatoid arthritis autoantigens by human dendritic cells and macrophages.人类树突状细胞和巨噬细胞对类风湿性关节炎自身抗原的差异性MHC II类介导的呈递
J Immunol. 2002 Dec 1;169(11):6625-33. doi: 10.4049/jimmunol.169.11.6625.
9
Progress in the immunogenetics of rheumatoid arthritis.类风湿关节炎免疫遗传学的进展。
Hosp Pract (Off Ed). 1995 Apr 15;30(4):77-81. doi: 10.1080/21548331.1995.11443184.
10
Use of soluble peptide-DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with rheumatoid arthritis.使用可溶性肽-DR4四聚体检测类风湿性关节炎患者中对软骨抗原有特异性的滑膜T细胞。
Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):291-6. doi: 10.1073/pnas.97.1.291.

引用本文的文献

1
Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination.在自身免疫性关节炎和脱髓鞘的小鼠模型中，表位扩展至瓜氨酸化抗原。
Arthritis Res Ther. 2008;10(5):R119. doi: 10.1186/ar2523. Epub 2008 Sep 30.
2
Recent developments in the immunobiology of rheumatoid arthritis.类风湿关节炎免疫生物学的最新进展
Arthritis Res Ther. 2008;10(2):204. doi: 10.1186/ar2370. Epub 2008 Mar 14.
3
Resting CD4+ effector memory T cells are precursors of bystander-activated effectors: a surrogate model of rheumatoid arthritis synovial T-cell function.

本文引用的文献

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On the occurrence of a factor in human serum activating the specific agglutintion of sheep blood corpuscles. 1939.关于人血清中一种能激活绵羊血细胞特异性凝集的因子的发现。1939年。
APMIS. 2007 May;115(5):422-38; discussion 439. doi: 10.1111/j.1600-0463.2007.apm_682a.x.
2
Cellular immunity to the G1 domain of cartilage proteoglycan aggrecan is enhanced in patients with rheumatoid arthritis but only after removal of keratan sulfate.类风湿性关节炎患者对软骨蛋白聚糖聚集蛋白聚糖G1结构域的细胞免疫增强，但仅在去除硫酸角质素后才会增强。
Arthritis Rheum. 1998 Jun;41(6):1019-25. doi: 10.1002/1529-0131(199806)41:6<1019::AID-ART8>3.0.CO;2-X.
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Arthritis Res Ther. 2008;10(2):R36. doi: 10.1186/ar2390. Epub 2008 Mar 19.
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Association of MHC and rheumatoid arthritis. HLA polymorphisms in phenotypic variants of rheumatoid arthritis.主要组织相容性复合体（MHC）与类风湿性关节炎的关联。类风湿性关节炎表型变异中的人类白细胞抗原（HLA）多态性。
Arthritis Res. 2000;2(3):212-6. doi: 10.1186/ar90. Epub 2000 Apr 19.
5
A new model for rheumatoid arthritis?类风湿关节炎的一种新模型？
Arthritis Res. 2000;2(2):85-9. doi: 10.1186/ar72. Epub 2000 Feb 9.
6
Blockade of endogenous interleukin 12 results in suppression of murine streptococcal cell wall arthritis by enhancement of interleukin 10 and interleukin 1Ra.内源性白细胞介素12的阻断通过增强白细胞介素10和白细胞介素1受体拮抗剂来抑制小鼠链球菌细胞壁关节炎。
Ann Rheum Dis. 2000 Mar;59(3):196-205. doi: 10.1136/ard.59.3.196.
Critical roles of glycosaminoglycan side chains of cartilage proteoglycan (aggrecan) in antigen recognition and presentation.
软骨蛋白聚糖（聚集蛋白聚糖）的糖胺聚糖侧链在抗原识别和呈递中的关键作用。
J Immunol. 1998 Apr 15;160(8):3812-9.
4
Induction of autoimmune arthritis in HLA-DR4 (DRB1*0401) transgenic mice by immunization with human and bovine type II collagen.通过用人和牛II型胶原蛋白免疫在HLA - DR4（DRB1*0401）转基因小鼠中诱导自身免疫性关节炎。
J Immunol. 1998 Mar 15;160(6):2573-8.
5
Characterization of the synovial T cell response to various recombinant Yersinia antigens in Yersinia enterocolitica-triggered reactive arthritis. Heat-shock protein 60 drives a major immune response.小肠结肠炎耶尔森菌引发的反应性关节炎中滑膜T细胞对各种重组耶尔森菌抗原反应的特征。热休克蛋白60引发主要免疫反应。
Arthritis Rheum. 1998 Feb;41(2):315-26. doi: 10.1002/1529-0131(199802)41:2<315::AID-ART16>3.0.CO;2-#.
6
Systemic antigen in the treatment of T-cell-mediated autoimmune diseases.全身性抗原在T细胞介导的自身免疫性疾病治疗中的应用。
Immunol Today. 1997 Dec;18(12):599-604. doi: 10.1016/s0167-5699(97)01171-7.
7
Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies.瓜氨酸是类风湿关节炎特异性自身抗体所识别的抗原决定簇的重要组成部分。
J Clin Invest. 1998 Jan 1;101(1):273-81. doi: 10.1172/JCI1316.
8
X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II.与来自人胶原蛋白II的肽复合的HLA - DR4（DRA*0101，DRB1*0401）的X射线晶体结构。
Immunity. 1997 Oct;7(4):473-81. doi: 10.1016/s1074-7613(00)80369-6.
9
Defective TCR-mediated signaling in synovial T cells in rheumatoid arthritis.类风湿关节炎中滑膜T细胞中TCR介导的信号传导缺陷。
J Immunol. 1997 Sep 15;159(6):2973-8.
10
Immunodominance is independent of structural constraints: each region within hen eggwhite lysozyme is potentially available upon processing of native antigen.免疫显性不依赖于结构限制：在天然抗原加工过程中，鸡蛋清溶菌酶内的每个区域都有可能被利用。
J Immunol. 1997 Sep 15;159(6):2574-9.