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Effect of adding selegiline to levodopa in early, mild Parkinson's disease. Formal systematic review of data on patients in all relevant trials is required.

作者信息

Counsell C

出版信息

BMJ. 1998 Dec 5;317(7172):1586.

PMID:9836669
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1114394/
Abstract
摘要

相似文献

1
Effect of adding selegiline to levodopa in early, mild Parkinson's disease. Formal systematic review of data on patients in all relevant trials is required.在早期轻度帕金森病中左旋多巴添加司来吉兰的效果。需要对所有相关试验中患者的数据进行正式系统评价。
BMJ. 1998 Dec 5;317(7172):1586.
2
Effect of adding selegiline to levodopa in early, mild Parkinson's disease. Evidence is insufficient to show that combined treatment increases mortality.在早期轻度帕金森病中左旋多巴加用司来吉兰的效果。证据不足表明联合治疗会增加死亡率。
BMJ. 1998 Dec 5;317(7172):1586-7.
3
Selegiline: a second look. Six years later: too risky in Parkinson's disease.司来吉兰：再审视。六年后：对帕金森病风险过高。
Prescrire Int. 2002 Aug;11(60):108-11.
4
Deprenyl and levodopa and Parkinson's disease progression.司来吉兰、左旋多巴与帕金森病进展
Ann Neurol. 1996 Aug;40(2):267-8. doi: 10.1002/ana.410400228.
5
Clinical inquiries. What is the best initial treatment of Parkinson's disease?临床咨询。帕金森病的最佳初始治疗方法是什么？
J Fam Pract. 2003 Nov;52(11):897-9.
6
Selegiline for Parkinson's disease.司来吉兰用于帕金森病。
Am Fam Physician. 1990 Feb;41(2):589-91.
7
Moderate Parkinson's disease. Strategies for maximizing treatment.中度帕金森病。优化治疗的策略。
Postgrad Med. 1996 Jan;99(1):52-4, 61-3, 67-8, passim.
8
Deprenyl in Parkinson's disease.
Ann Neurol. 1996 Aug;40(2):268-9. doi: 10.1002/ana.410400229.
9
Treatment of Parkinson's disease.帕金森病的治疗。
Aust Fam Physician. 1995 Sep;24(9):1685-7, 1690-2.
10
Early addition of selegiline to L-Dopa treatment is beneficial for patients with Parkinson disease.在左旋多巴治疗中早期添加司来吉兰对帕金森病患者有益。
Clin Neuropharmacol. 2010 Jan-Feb;33(1):1-4. doi: 10.1097/WNF.0b013e3181bbf45c.

引用本文的文献

1
Monoamine oxidase type B inhibitors in early Parkinson's disease: meta-analysis of 17 randomised trials involving 3525 patients.单胺氧化酶B型抑制剂用于早期帕金森病：17项涉及3525例患者的随机试验的荟萃分析。
BMJ. 2004 Sep 11;329(7466):593. doi: 10.1136/bmj.38184.606169.AE. Epub 2004 Aug 13.
2
Evaluating drug treatments for Parkinson's disease: how good are the trials?评估帕金森病的药物治疗：试验效果如何？
BMJ. 2002 Jun 22;324(7352):1508-11. doi: 10.1136/bmj.324.7352.1508.

本文引用的文献

1
Effect of selegiline on mortality in patients with Parkinson's disease: a meta-analysis.司来吉兰对帕金森病患者死亡率的影响：一项荟萃分析。
Neurology. 1998 Sep;51(3):825-30. doi: 10.1212/wnl.51.3.825.
2
Investigation by Parkinson's Disease Research Group of United Kingdom into excess mortality seen with combined levodopa and selegiline treatment in patients with early, mild Parkinson's disease: further results of randomised trial and confidential inquiry.英国帕金森病研究小组对早期轻度帕金森病患者联合使用左旋多巴和司来吉兰治疗时出现的超额死亡率进行的调查：随机试验和保密调查的进一步结果。
BMJ. 1998 Apr 18;316(7139):1191-6. doi: 10.1136/bmj.316.7139.1191.
3
Mortality in DATATOP: a multicenter trial in early Parkinson's disease. Parkinson Study Group.帕金森病早期治疗试验（DATATOP）中的死亡率：一项多中心试验。帕金森研究小组。
Ann Neurol. 1998 Mar;43(3):318-25. doi: 10.1002/ana.410430309.
4
Selegiline as the primary treatment of Parkinson's disease--a long-term double-blind study.司来吉兰作为帕金森病的主要治疗方法——一项长期双盲研究。
Acta Neurol Scand. 1997 Apr;95(4):211-8. doi: 10.1111/j.1600-0404.1997.tb00101.x.
5
The effects of early selegiline therapy on long-term levodopa treatment and parkinsonian disability: an interim analysis of a Norwegian--Danish 5-year study. Norwegian-Danish Study Group.早期司来吉兰治疗对长期左旋多巴治疗及帕金森病残疾的影响：一项挪威 - 丹麦5年研究的中期分析。挪威 - 丹麦研究小组
Mov Disord. 1997 Mar;12(2):175-82. doi: 10.1002/mds.870120207.
6
Effect of adding selegeline to levodopa in early, mild Parkinson's disease. Other studies have not shown increased mortality.在早期轻度帕金森病中左旋多巴加用司来吉兰的效果。其他研究未显示死亡率增加。
BMJ. 1996 Mar 16;312(7032):702; author reply 704-5.
7
Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: a longterm study.
J Neural Transm. 1985;64(2):113-27. doi: 10.1007/BF01245973.