[柔红霉素对急性白血病患者心脏毒性作用的多心电图评估]
[Polycardiographic evaluation of cardiotoxic effects of rubidomycin in patients with acute leukemia].
作者信息
Wodniecki J, Prochaczek F, Holowiecki J, Stella B
出版信息
Acta Haematol Pol. 1976 Jul-Sep;7(3):195-8.
PMID:983667
Abstract
In 6 out of 11 patients treated with rubidomycin deterioration of haemodynamic indices was observed including prolongation of the pressure rise subperiod, isometric contarction subperiod and reduction of mechanical index. These changes appeared already after the first administration of the drug and were followed in 4 cases by signs of circulatory failure.
摘要
在接受柔红霉素治疗的11例患者中，有6例观察到血流动力学指标恶化，包括压力上升期、等长收缩期延长以及机械指数降低。这些变化在首次用药后就已出现，4例随后出现循环衰竭迹象。
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