Wakabayashi T, Asano M, Kurono C, Ozawa T, Kishimoto H
Acta Pathol Jpn. 1976 Jul;26(4):457-66. doi: 10.1111/j.1440-1827.1976.tb00503.x.
Effect of bovine serum albumin on coupling efficiency of mitochondria isolated from the zona glomerulosa of the bovine adrenal cortex in various media was examined polarographically and electron microscopically. Albumin restored the coupling efficiency of mitochondria isolated from the zona glomerulosa regardless of isolation media when succinate or malate was oxidizable substrate. Respiratory controls greater than 5 were obtained. Albumin, however, had no effect when glutamate, beta-hydroxybutylate and pyruvate were the oxidizable substrates. The conditions have been found under which mitochondria of the zona glomerulosa stay in the orthodox configuration and yet coupled.
采用极谱法和电子显微镜法，研究了牛血清白蛋白对在各种介质中从牛肾上腺皮质球状带分离的线粒体偶联效率的影响。当琥珀酸或苹果酸为可氧化底物时，无论分离介质如何，白蛋白均可恢复从球状带分离的线粒体的偶联效率。呼吸控制率大于5。然而，当谷氨酸、β-羟基丁酸酯和丙酮酸为可氧化底物时，白蛋白没有作用。已经发现了球状带线粒体保持正统构型且偶联的条件。
