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关于匙羹藤酸对仓鼠和大鼠的影响。

On the effects of gymnemic acid in the hamster and rat.

作者信息

Hellekant G, Gopal V

出版信息

Acta Physiol Scand. 1976 Oct;98(2):136-42. doi: 10.1111/j.1748-1716.1976.tb00233.x.

DOI:10.1111/j.1748-1716.1976.tb00233.x
PMID:983724
Abstract

The gustatory activity of the chorda tympani proper nerve has been recorded before and after the application of gymnemic acid to the tongue of hamster and rat. Concentrations of pure gymnemic acid ranging from 1 mg/ml to 10 mg/ml have been used. In the hamster gymnemic acid suppressed the response to solutions of sucrose especially, but it also caused, at higher concentrations, a general suppression of the tast response. The depression caused in the response to sucrose was directly related to the strength of the gymnemic acid and inversely to that of the sucrose solution. In the rat a suppression of the response to saccharin was obtained but no suppression of the taste response to sucrose by gymnemic acid was observed.

摘要

在将匙羹藤酸涂抹于仓鼠和大鼠的舌头前后,记录了鼓索神经本身的味觉活动。使用了浓度范围为1毫克/毫升至10毫克/毫升的纯匙羹藤酸。在仓鼠中,匙羹藤酸尤其抑制了对蔗糖溶液的反应,但在较高浓度下,它也会导致味觉反应的普遍抑制。对蔗糖反应的抑制与匙羹藤酸的强度直接相关,与蔗糖溶液的强度呈反比。在大鼠中,获得了对糖精反应的抑制,但未观察到匙羹藤酸对蔗糖味觉反应的抑制。

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