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肝细胞癌的肝移植

Liver transplantation for hepatocellular carcinoma.

作者信息

Ranjan D, Johnston T D

机构信息

Department of Surgery, University of Kentucky, Lexington, USA.

出版信息

Hepatogastroenterology. 1998 Sep-Oct;45(23):1369-74.

PMID:9840067
Abstract

Liver transplantation (LT) for hepatocellular carcinoma (HCC) has been controversial, however, with increasing experience the results of the procedure in these patients have improved. Earlier reports of poor result may have been secondary to advanced tumor and poor patient selection. Careful patient selection and preoperative assessment of tumor characteristic is essential before offering LT to these patients. Results of LT in carefully selected cases may be similar to patients receiving LT for other reasons. In cirrhotic patients LT may offer a better long-term survival than liver resection.

摘要

肝细胞癌(HCC)的肝移植(LT)一直存在争议,然而,随着经验的增加,该手术在这些患者中的结果有所改善。早期关于结果不佳的报道可能是由于肿瘤进展和患者选择不当所致。在为这些患者提供肝移植之前,仔细的患者选择和肿瘤特征的术前评估至关重要。在精心挑选的病例中,肝移植的结果可能与因其他原因接受肝移植的患者相似。在肝硬化患者中,肝移植可能比肝切除术提供更好的长期生存率。

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