产后及流产后宫颈和子宫腔对减毒风疹病毒感染的易感性。

The susceptibility of the postpartum and postabortal cervix and uterine cavity to infection with attenuated rubella virus.

作者信息

Bolognese R J, Corson S L, Fuccillo D A, Traub R

出版信息

Am J Obstet Gynecol. 1976 Jun 15;125(4):525-7. doi: 10.1016/0002-9378(76)90370-7.

Abstract

To determine the susceptibility of the postpartum and postabortal genital tract to infection with attenuated rubella virus, 30 patients with negative hemagglutination inhibition (HI) titers were studied. Following inoculation with Cendehill or RA 27/3 vaccine, viral cultures of the cervix and uterine cavity were obtained with blood specimens to evaluate serologic conversion. Attenuated rubella virus was not isolated in any patient; seropositive conversion was achieved in 24 women. The significance of these findings related to wild rubella virus infection is discussed.

摘要

为了确定产后和流产后生殖道对减毒风疹病毒感染的易感性，对30名血凝抑制（HI）效价为阴性的患者进行了研究。在用森德希尔（Cendehill）或RA 27/3疫苗接种后，采集宫颈和宫腔的病毒培养物以及血标本以评估血清学转化。在任何患者中均未分离出减毒风疹病毒；24名女性实现了血清学阳转。讨论了这些发现与野生风疹病毒感染相关的意义。