Athanassiadi K, Apostolakis E, Kalavrouziotis G, Charitos C, Karamichali E, Kakavos D, Lolas C
Department of Cardiac Surgery, "Evangelismos" General Hospital, Papagou Ave. 119, 15773 Zografou, Athens, Greece.
World J Surg. 1999 Jan;23(1):64-7. doi: 10.1007/s002689900566.
Postinfarction ventricular septal defect (PIVSD) remains a surgical challenge resulting in devastating mortality rates. We present our 10-year experience in surgical management of this catastrophic complication of acute myocardial infarction. During a decade (1987-1996) 14 patients with PIVSD were treated surgically in our department. There were 10 men and 4 women, ranging in age from 51 to 78 years. The rupture occurred within the first 4 days after the infarction in most cases (n = 10). Eight patients were supported perioperatively by intraaortic balloon counterpulsation (IABP). In all cases the surgical technique included infarctectomy and ventricular septum reconstruction with synthetic patches. Coronary artery bypass grafting was synchronously performed in four patients. Seven patients died perioperatively (mortality rate 50%) due to heart failure and to multiple organ failure. The most frequent complications were low cardiac output syndrome, hemorrhage, and respiratory and renal insufficiency. The PIVSD needs urgent surgical intervention with the patient hemodynamically stable after cardiac catheterization. Long-term results are favorable for survivors.
心肌梗死后室间隔缺损(PIVSD)仍然是一个手术挑战,导致极高的死亡率。我们介绍我们在手术治疗急性心肌梗死这一灾难性并发症方面的10年经验。在十年间(1987 - 1996年),我们科室对14例PIVSD患者进行了手术治疗。其中男性10例,女性4例,年龄在51岁至78岁之间。大多数病例(n = 10)的室间隔破裂发生在心肌梗死后的前4天内。8例患者在围手术期接受了主动脉内球囊反搏(IABP)支持。所有病例的手术技术均包括梗死灶切除术和用合成补片重建室间隔。4例患者同时进行了冠状动脉旁路移植术。7例患者因心力衰竭和多器官衰竭在围手术期死亡(死亡率50%)。最常见的并发症是低心排血量综合征、出血以及呼吸和肾功能不全。PIVSD需要在心脏导管检查后患者血流动力学稳定时进行紧急手术干预。幸存者的长期预后良好。