与不同伴侣有多次性接触的年轻男同性恋者中人类疱疹病毒8型血清阳性率增加。

Increased human herpesvirus 8 seroprevalence in young homosexual men who have multiple sex contacts with different partners.

作者信息

Blackbourn D J, Osmond D, Levy J A, Lennette E T

机构信息

Department of Medicine, University of California, San Francisco, USA.

出版信息

J Infect Dis. 1999 Jan;179(1):237-9. doi: 10.1086/314570.

DOI:10.1086/314570

PMID:9841846

Abstract

The objective of this study was to evaluate the behavioral risks that are associated with human herpesvirus 8 (HHV-8) infection in a cohort of young homosexual men. Seventy-nine subjects (ages 22-33 years) who completed a questionnaire about their sexual and drug use behavior over the preceding year were recruited from the San Francisco Young Men's Health Study. Plasma samples were tested for anti-HHV-8 antibodies using an indirect IFA. Thirty-eight subjects (48.1%) were infected with HHV-8. HHV-8 infection was significantly linked to an increasing number of male sex partners (P=.025, Mantel-Haenszel chi2 test for trend), suggesting a strong association between HHV-8 infection and multiple homosexual contacts.

摘要

本研究的目的是评估一群年轻同性恋男性中与人类疱疹病毒8型（HHV-8）感染相关的行为风险。从旧金山青年男性健康研究中招募了79名受试者（年龄在22 - 33岁之间），他们完成了一份关于前一年性行为和药物使用行为的问卷。使用间接免疫荧光法检测血浆样本中的抗HHV-8抗体。38名受试者（48.1%）感染了HHV-8。HHV-8感染与男性性伴侣数量的增加显著相关（P = 0.025，Mantel-Haenszel卡方趋势检验），表明HHV-8感染与多次同性恋接触之间存在密切关联。