Hiro T, Hall P, Maiello L, Itoh A, Colombo A, Jang Y T, Salmon S M, Tobis J M
University of California Irvine, Cuore Columbus, and CVIS, Inc, Irvine, CA, USA.
Am Heart J. 1998 Dec;136(6):1017-20. doi: 10.1016/s0002-8703(98)70158-9.
Intravascular ultrasound imaging (IVUS) is limited by the size of the imaging catheter. To facilitate imaging before and during interventions, a 30-MHz ultrasonic imaging device was developed that is the same dimension as a 0.018-inch guide wire. The purpose of this study was to evaluate the clinical feasibility of this device.
The imaging core was tested in 8 patients with the use of a monorail guiding sheath that was advanced through a 7F catheter. In addition, after coronary interventions, the standard guide wire was removed, the imaging core was placed inside a compatible balloon, and imaging was performed. In 4 patients, imaging was also performed with a standard 3.2F IVUS catheter. The lumen-plaque interface and the media-plaque interface were clearly visualized in all patients. There was no detectable loss in image quality between the new imaging device and the larger IVUS catheter, and measurements of lumen cross-sectional area were not statistically different.
Improvements in manufacturing technology have permitted the development of a mechanically rotating ultrasound imaging core 0.018 inches in diameter. It is compatible with current balloon catheters without degradation of image quality.
血管内超声成像（IVUS）受成像导管尺寸限制。为便于在介入治疗前及治疗过程中进行成像，研发了一种与0.018英寸导丝尺寸相同的30兆赫超声成像设备。本研究旨在评估该设备的临床可行性。
使用通过7F导管推进的单轨引导鞘管，在8例患者中对成像核心进行了测试。此外，在冠状动脉介入治疗后，移除标准导丝，将成像核心置于兼容球囊内并进行成像。在4例患者中，还使用标准3.2F IVUS导管进行了成像。所有患者的管腔-斑块界面和中膜-斑块界面均清晰可见。新成像设备与较大的IVUS导管之间的图像质量无明显下降，管腔横截面积测量结果无统计学差异。
制造技术的进步使得能够研发出直径为0.018英寸的机械旋转超声成像核心。它与当前球囊导管兼容，且图像质量无下降。
