Schwarzenberg H, Müller-Hülsbeck S, Glüer C C, Steffens J C, Heller M
Department of Radiology, Christian-Albrechts-Universität zu Kiel, Germany.
AJR Am J Roentgenol. 1998 Dec;171(6):1627-30. doi: 10.2214/ajr.171.6.9843301.
The purpose of this study was to use intravascular sonography to evaluate neointima formation, plaque location, and the performance of self-expanding nitinol (Memotherm) stents in iliac arteries.
Seventeen patients (mean age, 64+/-9.4 years) with stenoses or occlusions of the common (n = 12) or external (n = 5) iliac artery were treated with 21 Memotherm stents (mean diameter +/- SD, 8.9+/-1.3 mm; mean length, 53+/-20.9 mm). Four patients had two stents each. Intravascular sonography was performed 13+/-6 months after stent implantation. Maximum thickness of neointima and maximum cross-sectional plaque area were measured. Qualitative analysis of plaque composition and lesion topography were also assessed.
Intravascular sonography revealed 22.1%+/-17.3% maximum percentage of restenosis, and maximum plaque area was found to be 11.2+/-10 mm2. Only hypoechogenic in-stent lesions (soft plaques) were found. Seven (33%) incomplete stent expansions and two (10%) incomplete appositions of the stent to the vessel wall were revealed by intravascular sonography.
Iliac artery Memotherm stents generally showed moderate in-stent restenosis with uniform neointima distribution. Incomplete stent expansion was detected in one third of all implanted stents.
本研究旨在使用血管内超声评估髂动脉中新生内膜形成、斑块位置以及自膨式镍钛合金（Memotherm）支架的性能。
17例患者（平均年龄64±9.4岁），其中12例为髂总动脉狭窄或闭塞，5例为髂外动脉狭窄或闭塞，共植入21枚Memotherm支架（平均直径±标准差，8.9±1.3 mm；平均长度，53±20.9 mm）。4例患者各植入2枚支架。在支架植入后13±6个月进行血管内超声检查。测量新生内膜的最大厚度和斑块最大横截面积。还对斑块成分和病变形态进行了定性分析。
血管内超声显示最大再狭窄率为22.1%±17.3%，最大斑块面积为11.2±10 mm²。仅发现支架内低回声病变（软斑块）。血管内超声显示7例（33%）支架扩张不完全，2例（10%）支架与血管壁贴靠不完全。
髂动脉Memotherm支架一般显示出中度的支架内再狭窄，新生内膜分布均匀。在所有植入的支架中，三分之一检测到支架扩张不完全。
