Montazem A
Department of Oral and Maxillofacial Surgery, Mount Sinai School of Medicine, New York, NY 10029, USA.
Mt Sinai J Med. 1998 Oct-Nov;65(5-6):388-92.
Antibiotic prophylaxis for the prevention of infective endocarditis related to dental therapy is a widespread therapeutic intervention. Recently, updated and revised guidelines on this treatment modality have been set forth in the form of consensus statements. It is evident that the risk of spontaneous bacteremia is much greater in a diseased oral cavity than it is in a healthy oral cavity. Perhaps most important in the prevention of infective endocarditis is early identification of at-risk patients and prompt referral to oral health specialists for comprehensive evaluation and treatment. The judicious use of antibiotic prophylaxis for prevention of infective endocarditis, in conjunction with optimal oral health care, should serve to minimize the adverse effects of antibiotic therapy and at the same time reduce the significant morbidity and mortality associated with these infections.
抗生素预防用于预防与牙科治疗相关的感染性心内膜炎是一种广泛应用的治疗干预措施。最近，以共识声明的形式发布了关于这种治疗方式的更新和修订指南。显然，患病口腔中自发性菌血症的风险比健康口腔中要大得多。预防感染性心内膜炎最重要的可能是早期识别高危患者，并及时转诊至口腔健康专家处进行全面评估和治疗。明智地使用抗生素预防感染性心内膜炎，结合最佳的口腔卫生保健，应有助于将抗生素治疗的不良反应降至最低，同时降低与这些感染相关的显著发病率和死亡率。
