Birch J F, White S A, Berry D P, Veitch P S
Department of Surgery, Leicester General Hospital, UK.
Dis Esophagus. 1998 Jul;11(3):172-6. doi: 10.1093/dote/11.3.172.
This retrospective study was undertaken to assess the cost-benefit aspects of self expanding metal stents (SEMS), versus Atkinson Tubes (AT) in the palliation of obstructing esophageal tumors. Over a 4 year period, 50 patients received palliative endoscopic intubation for inoperable esophageal malignancy. Patients either received an AT or a newer, but more expensive, SEMS, both inserted under general anaesthetic. Both patients cohorts were assessed in terms of the severity of their dysphagia and scored according to Atkinson and Fergusons' classification both pre- and post-operatively. Other factors that were considered included length of hospital stay, number of interventions, admission to the Intensive Treatment Unit (ITU), and rates of post-operative complication. The majority of tumors were either adenocarcinoma or squamous cell carcinoma. The location of the tumors (upper, middle or lower) were similar in each group as was the mean length of tumor being 7 cms in SEMS and 5 cms in AT. There were significantly more complications in the AT group compared to the SEMS group (p < 0.05). The most common complications in the AT group were tube displacement (21%), tumor overgrowth (26%) and esophageal perforation (13%). In contrast complications of the SEMS group were tumor overgrowth (15%) and esophageal perforation (8%). Mean hospital stay was 3 (1-30) days for SEMS and 8 (2-122) days for AT (p < 0.05). The median total cost of hospital stay was 1745 pounds (1027-5424) for SEMS versus 2349 pounds (1163-24,481) for AT.
本回顾性研究旨在评估自膨式金属支架(SEMS)与阿特金森管(AT)在缓解食管肿瘤梗阻方面的成本效益。在4年期间,50例患者因无法手术的食管恶性肿瘤接受了姑息性内镜插管。患者要么接受阿特金森管,要么接受更新但更昂贵的自膨式金属支架,两者均在全身麻醉下插入。两个患者队列均根据吞咽困难的严重程度进行评估,并在术前和术后根据阿特金森和弗格森分类进行评分。其他考虑的因素包括住院时间、干预次数、入住重症治疗病房(ITU)情况以及术后并发症发生率。大多数肿瘤为腺癌或鳞状细胞癌。每组肿瘤的位置(上、中或下)相似,自膨式金属支架组肿瘤的平均长度为7厘米,阿特金森管组为5厘米。与自膨式金属支架组相比,阿特金森管组的并发症明显更多(p<0.05)。阿特金森管组最常见的并发症是管子移位(21%)、肿瘤过度生长(26%)和食管穿孔(13%)。相比之下,自膨式金属支架组的并发症是肿瘤过度生长(15%)和食管穿孔(8%)。自膨式金属支架组的平均住院时间为3(1 - 30)天,阿特金森管组为8(2 - 122)天(p<0.05)。自膨式金属支架组住院总费用中位数为1745英镑(1027 - 5424),阿特金森管组为2349英镑(1163 - 24481)。