Guyton C L, Missaghi E, Marshall P M
Am J Vet Res. 1976 Nov;37(11):1287-9.
Three Charolais calves were treated orally with [14C] phenothiazine. The amount of radioactivity excreted in the urine and feces was measured. The average quantity of the excreted dose recovered was divided equally between the urine and the feces. The radioactivity found in the feces and gastrointestinal tract was variable between the animals, but the urinary radioactivity was constant. Only a small amount of the administered dose was retained by selected organs, with the liver and kidneys accounting for most of that amount. These organs also had tissue-to-blood ratios of radioactivity greater than unity, whereas the other tissues had ratios close to unity. Essentially complete recovery of the administered radioactive dose was achieved.
给三头夏洛来牛犊口服[14C]吩噻嗪。测量尿液和粪便中排出的放射性量。回收的排出剂量的平均量在尿液和粪便中平均分配。不同动物粪便和胃肠道中的放射性不同，但尿液中的放射性是恒定的。只有少量给药剂量被选定器官保留，其中肝脏和肾脏占了大部分。这些器官的放射性组织与血液比值也大于1，而其他组织的比值接近1。给药的放射性剂量基本完全回收。
