McDermott M M, Liu K, Guralnik J M, Martin G J, Criqui M H, Greenland P
Department of Medicine and the Department of Preventive Medicine, Northwestern University Medical School, Chicago, IL 60611, USA.
J Vasc Surg. 1998 Dec;28(6):1072-81. doi: 10.1016/s0741-5214(98)70034-5.
The Walking Impairment Questionnaire (WIQ) was designed to measure community walking ability in patients with peripheral arterial disease (PAD) and intermittent claudication. We compared the WIQ scores to objective measures of walking in a heterogeneous group of patients with and without PAD.
The study was designed as a cross-sectional study, with the setting in an academic medical center. The subjects were patients with PAD (n = 145) who were identified from a noninvasive vascular laboratory at an academic medical center. The patients without PAD (n = 65) were identified from a general medicine practice. The average number of comorbidities was 2.03 for patients with PAD and 1.52 for patients without PAD. Among the patients with PAD, 28% had classical intermittent claudication symptoms and 55% had exertional leg symptoms other than claudication. The main outcome measures were the WIQ estimates of the patient-reported walking distance and walking speed on a scale of 0 to 100. Walking endurance was measured objectively with the 6-minute walk. Walking velocity was measured with a 4-m walk. PAD and PAD severity were defined with the ankle brachial index.
The Spearman rank correlation coefficients (rho) between the WIQ distance score and the 6-minute walk score were 0.557 among patients with PAD (P <.001) and 0.484 among patients without PAD (P <.001). The correlation coefficients between the WIQ speed score and the usual-paced 4-m walk score were 0.528 among patients with PAD (P <.001) and 0.524 among patients without PAD (P <.001). The correlations were not affected by the presence versus the absence of intermittent claudication, by PAD severity, or by the presence of 2 or more versus less than 2 comorbid illnesses. The WIQ scores in the highest and lowest quartiles were the most closely associated with the objective measures of function.
The WIQ is a valid measure of community walking ability in a heterogeneous group of patients with and without PAD. The WIQ discriminates best among patients in the highest and the lowest quartiles of walking speed and endurance.
步行障碍问卷(WIQ)旨在测量外周动脉疾病(PAD)和间歇性跛行患者的社区步行能力。我们将WIQ评分与一组患有和未患有PAD的异质性患者的客观步行测量结果进行了比较。
本研究设计为横断面研究,在一所学术医疗中心进行。研究对象为从一所学术医疗中心的无创血管实验室确诊的PAD患者(n = 145)。未患PAD的患者(n = 65)来自普通内科门诊。PAD患者的平均合并症数为2.03,未患PAD的患者为1.52。在PAD患者中,28%有典型的间歇性跛行症状,55%有除跛行外的运动性腿部症状。主要结局指标是患者报告的步行距离和步行速度的WIQ估计值,范围为0至100。步行耐力通过6分钟步行试验进行客观测量。步行速度通过4米步行试验进行测量。PAD及PAD严重程度通过踝臂指数进行定义。
在PAD患者中,WIQ距离评分与6分钟步行评分之间的Spearman等级相关系数(rho)为0.557(P <.001),在未患PAD的患者中为0.484(P <.001)。在PAD患者中,WIQ速度评分与常规步速4米步行评分之间的相关系数为0.528(P <.001),在未患PAD的患者中为0.524(P <.001)。这些相关性不受间歇性跛行的有无、PAD严重程度或合并症数是否为2种或更多与少于2种的影响。WIQ评分处于最高和最低四分位数的患者与功能的客观测量结果相关性最强。
WIQ是测量一组患有和未患有PAD的异质性患者社区步行能力的有效指标。WIQ在步行速度和耐力处于最高和最低四分位数的患者中区分能力最强。