Magro G, Bisceglia M, Pasquinelli G
Servizio di Anatomia Patologica, Istituto di Anatomia Patologica, Catania, Italy.
Ann Diagn Pathol. 1998 Oct;2(5):306-11. doi: 10.1016/s1092-9134(98)80023-3.
We report a rare case of "benign spindle cell tumor of the breast with prominent adipocytic component" and present a review of the literature on the topic. The close morphologic resemblance with myofibroblastoma and spindle cell lipoma of the breast is emphasized and used as a starting point for diagnostic and histogenetic considerations. Although immunocytochemistry and electron microscopy showed features favoring a diagnosis of spindle cell lipoma, they were not conclusive. The tumor described here contributes to widen the spectrum of the benign spindle cell tumors of the breast variously named "benign spindle cell tumor," myofibroblastoma, spindle cell lipoma, and fibroma. It is important to distinguish this lesion from spindle cell metaplastic carcinoma and aggressive fibromatosis.
我们报告了一例罕见的“乳腺良性梭形细胞瘤伴显著脂肪细胞成分”病例，并对该主题的文献进行了综述。强调了其与乳腺肌纤维母细胞瘤和梭形细胞脂肪瘤在形态学上的密切相似性，并以此作为诊断和组织发生学考虑的起点。尽管免疫细胞化学和电子显微镜检查显示出支持梭形细胞脂肪瘤诊断的特征，但并不具有决定性。本文描述的肿瘤有助于拓宽乳腺良性梭形细胞瘤的谱系，这些肿瘤有不同的名称，如“良性梭形细胞瘤”、肌纤维母细胞瘤、梭形细胞脂肪瘤和纤维瘤。将此病变与梭形细胞化生癌和侵袭性纤维瘤病区分开来很重要。
