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[溶液pH值对不同程度拉伸的大鼠肠系膜动脉离体节段反应性的影响]

[Effect of solution pH on the reactivity of the isolated segment of the rat mesenteric artery subjected stretching of various degree].

作者信息

Iartsev V N, Karachentseva O V, Dvoretskiĭ D P

机构信息

Pavlov Institute of Physiology of the Russian Acad. Sci., St. Petersburg, Russia.

出版信息

Ross Fiziol Zh Im I M Sechenova. 1998 Aug;84(8):775-82.

PMID:9845895
Abstract

Experiments on the rat mesenteric artery's segments at different degrees of its stretching showed no influence of acidosis or alkalosis on the vessel wall tension within a wide range of pH (7.8-6.6). Acidification of the solution (7.0 or 6.6) inhibited the vessel response to noradrenaline or electrical field stimulation (EFS). On the contrary, the acidification potentiated a constriction caused by the EFS at a high level of vascular tone.

摘要

对大鼠肠系膜动脉不同拉伸程度的节段进行的实验表明,在较宽的pH范围(7.8 - 6.6)内,酸中毒或碱中毒对血管壁张力没有影响。溶液酸化(至pH 7.0或6.6)会抑制血管对去甲肾上腺素或电场刺激(EFS)的反应。相反,在高血管张力水平下,酸化会增强由EFS引起的血管收缩。

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