Luria M H, Knoke J D, Margolis R M, Hendricks F H, Kuplic J B
Ann Intern Med. 1976 Nov;85(5):561-5. doi: 10.7326/0003-4819-85-5-561.
A prognostic index for 2-year survival after recovery from acute myocardial infarction was constructed from variables obtained during its course. One hundred ten of 143 patients survived 2 years, and 27 of 33 patients died of cardiac-related causes. Univariate analysis showed that 12 variables were significantly different between the surviving and nonsurviving groups. Discriminant analysis indicated five variables with meaningful predictive value to be included in a prognostic index: admission systolic blood pressure; highest blood urea nitrogen level in the cardiac care unit: atrial arrhythmias in the cardiac care unit; angina pectoris for more than 3 months or a previous myocardial infarction; and more than one ventricular ectopic beat per hour recorded on a dynamic electrocardiogram during the 17th to 24th hospital day. The prognostic index emphasizes the importance of extensive myocardial impairment and provides a means for identifying patients at risk of early mortality.
基于急性心肌梗死恢复过程中获取的变量构建了一个预测急性心肌梗死后2年生存率的指数。143例患者中有110例存活了2年，33例患者中有27例死于心脏相关原因。单因素分析显示，存活组和非存活组之间有12个变量存在显著差异。判别分析表明，有5个具有有意义预测价值的变量可纳入预后指数：入院时收缩压；心脏监护病房中最高血尿素氮水平；心脏监护病房中的房性心律失常；心绞痛持续3个月以上或既往心肌梗死；以及在住院第17至24天动态心电图记录显示每小时有一个以上室性早搏。该预后指数强调了广泛心肌损伤的重要性，并提供了一种识别有早期死亡风险患者的方法。
