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爱沙尼亚1992 - 1994年医学出生登记:危险因素与围产期死亡率的关联

Estonian medical birth registry 1992-1994: association of risk factors with perinatal mortality.

作者信息

Karro H, Rahu M, Gornoi K, Baburin A

机构信息

Women's Clinic, University of Tartu, Estonia.

出版信息

Eur J Obstet Gynecol Reprod Biol. 1998 Oct;80(2):151-6. doi: 10.1016/s0301-2115(98)00119-5.

Abstract

OBJECTIVE

To investigate the association of different maternal sociodemographic characteristics and infant sex with perinatal mortality among primiparas and multiparas.

STUDY DESIGN

Analysis of routine data from the Estonian Medical Birth Registry covering the whole of Estonia. A total of 47 358 infants (including stillborns) with a birth weight 1000 g or more from 1992 through 1994 were studied. Perinatal mortality rate, crude odds ratio (OR) and adjusted OR (calculated by a logistic regression model) were used to evaluate the association. OR values were adjusted for maternal age at delivery, maternal ethnicity, educational level, residence, marital status, smoking status, history of previous abortion and infant sex.

RESULTS

The perinatal mortality rate was 12.2 per 1000 total births among primiparous and 14.3 among multiparous women. The highest adjusted ORs of perinatal deaths were found in older (35 years and over) primiparas (1.78; 95% confidence interval (CI 0.88-3.57)) and multiparas (1.81; 95% CI 1.29-2.55), in unmarried (single) primiparas (1.59; 95% CI 1.14-2.20) and multiparas (1.98; 95% CI 1.29-3.05), in smoking primiparas (1.69; 95% CI 1.09-2.63) and multiparas (1.51; 95% CI 1.02-2.25), and in multiparas with unknown smoking status (1.98; 95% CI 1.18-3.33).

CONCLUSION

The study provides further evidence that perinatal mortality is positively associated with increased maternal age, unmarried (single) status and smoking.

摘要

目的

探讨初产妇和经产妇不同的母亲社会人口学特征及婴儿性别与围产期死亡率之间的关联。

研究设计

对爱沙尼亚医疗出生登记处涵盖整个爱沙尼亚的常规数据进行分析。研究了1992年至1994年期间出生体重1000克及以上的47358名婴儿(包括死产儿)。采用围产期死亡率、粗比值比(OR)和调整后的OR(通过逻辑回归模型计算)来评估这种关联。OR值根据产妇分娩时年龄、产妇种族、教育水平、居住地、婚姻状况、吸烟状况、既往流产史和婴儿性别进行了调整。

结果

初产妇的围产期死亡率为每1000例总出生数中有12.2例,经产妇为14.3例。围产期死亡调整后最高的OR值出现在年龄较大(35岁及以上)的初产妇(1.78;95%置信区间(CI)0.88 - 3.57)和经产妇(1.81;95%CI 1.29 - 2.55)、未婚(单身)初产妇(1.59;95%CI 1.14 - 2.20)和经产妇(1.98;95%CI 1.29 - 3.05)、吸烟初产妇(1.69;95%CI 1.09 - 2.63)和经产妇(1.51;95%CI 1.02 - 2.25)以及吸烟状况不明的经产妇(1.98;95%CI 1.18 - 3.33)中。

结论

该研究进一步证明围产期死亡率与产妇年龄增加、未婚(单身)状态和吸烟呈正相关。

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