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[实验性旋毛虫病(IV),环磷酰胺对18日龄旋毛虫成虫移植作用的研究(作者译)]

[Experimental trichinasis (IV), study of the action of cyclophosphamide on the transplantation of 18 days old adults of T. spiralis (author's transl)].

作者信息

Poirot J L, Lancastre F, Mougeot G, Depernet D

出版信息

Ann Parasitol Hum Comp. 1976 Jul-Aug;51(4):447-52.

PMID:984672
Abstract

The survival and the transplantation of adult trichinae collected in cyclophosphamide treated and untreated mice were studied. 1) The worms'burden harbored by treated mice on the 18th day after the infestation is from 4 to 5 times higher than in untreated ones. The sex ratio is here around one instead of 1/2 in the control lot of mice. 2) The female worms parasitic in treated mice continue to lay larvae. When these adult are transplanted in the gut of treated mice they seem give a greater number of larvae than if they are put in the gut of normal mice.

摘要

研究了在经环磷酰胺处理和未处理的小鼠体内收集的成年旋毛虫的存活及移植情况。1)感染后第18天,经处理的小鼠体内的虫负荷比未处理的小鼠高4至5倍。此处的性别比约为1,而对照小鼠组为1/2。2)寄生在经处理小鼠体内的雌虫继续产幼虫。当将这些成虫移植到经处理小鼠的肠道中时,它们产生的幼虫数量似乎比移植到正常小鼠肠道中时更多。

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