Stabholz A, Mann J, Agmon S, Soskolne W A
Hebrew University-Hadassah Faculty of Dental Medicine, Department of Community Dentistry, Jerusalem, Israel.
J Clin Periodontol. 1998 Nov;25(11 Pt 1):872-8. doi: 10.1111/j.1600-051x.1998.tb02384.x.
The reported prevalence of localized juvenile periodontitis (LJP) amongst teenagers and young adults varies greatly. The etiology of LJP has been related to Actinobacillus actinomycetemcomitans (Aa), and it has also been suggested that there may be a transmission of Aa within families resulting in the familial distribution of the disease. This study describes the high prevalence of LJP in adolescents, 12-20 years of age, from a group of nuclear families living and functioning in a closed, closely knit community. The survey was carried out on a population of teenagers that had attended the same school and their siblings. All students attending that school and their siblings were examined. They were given a periodontal examination and a questionnaire relating to their demographic details and their personal oral hygiene habits. The periodontal examination was limited to the incisors and first molar teeth. Plaque index (PlI), gingival index (GI), the presence or absence of bleeding on probing (BOP), probing pocket depth (PPD) and recession were measured. All patients having at least two of the examined sites with probing pocket depth > or =5 mm or one site > or =6 mm were considered as possible sufferers from LJP and had a full mouth periapical radiographic survey carried out using a paralleling technique to confirm the diagnosis. At the sites with probing pocket depth > or =5 mm, a Shei ruler was used to measure the % of the root coronal to the alveolar bone. A cut off point of > or =20% was used as a measure of true bone loss confirming the clinical diagnosis of LJP. 86 individuals from 30 families comprised the population of interest. There were 44 males and 42 females with a mean age of 14.7+/-2.3. Of the 86 individuals examined, 33 individuals from 15 families were diagnosed as having LJP (38.4%). None of the individuals examined showed any evidence of the generalized form of juvenile periodontitis. The mean age of the LJP patients was 15+/-2.3 yrs. with a 1:1.75 male to female ratio. Except for 2 pairs of families with genetic ties, no familial connections could be traced between the different nuclear families affected by LJP despite repeated and intensive questioning. There were no significant differences in the PlI and the GI between the groups while the LJP group had significantly higher BOP, PPD and PAL than the non-LJP group. These finding strongly suggest an environmental influence in the etiology of the disease.
据报道，青少年和青年中局限性青少年牙周炎（LJP）的患病率差异很大。LJP的病因与伴放线放线杆菌（Aa）有关，也有人提出Aa可能在家庭内部传播，导致该病呈家族性分布。本研究描述了在一个封闭、紧密的社区中生活和活动的一组核心家庭中，12至20岁青少年中LJP的高患病率。该调查针对的是就读于同一所学校的青少年及其兄弟姐妹。对该校所有学生及其兄弟姐妹进行了检查。他们接受了牙周检查，并填写了一份关于其人口统计学细节和个人口腔卫生习惯的问卷。牙周检查仅限于门牙和第一磨牙。测量了菌斑指数（PlI）、牙龈指数（GI）、探诊出血（BOP）情况、探诊袋深度（PPD）和牙龈退缩情况。所有至少有两个检查部位探诊袋深度≥5mm或一个部位≥6mm的患者被视为可能患有LJP，并采用平行投照技术进行全口根尖片检查以确诊。在探诊袋深度≥5mm的部位，使用谢伊尺测量牙根在牙槽骨冠方的比例。以≥20%作为真正骨吸收的衡量标准，以确诊LJP的临床诊断。来自30个家庭的86人构成了研究对象。其中男性44人，女性42人，平均年龄为14.7±2.3岁。在接受检查的86人中，来自15个家庭的33人被诊断患有LJP（38.4%）。所有接受检查的个体均未表现出青少年牙周炎的全身性形式的任何证据。LJP患者的平均年龄为15±2.3岁，男女比例为1:1.75。除了2对有血缘关系的家庭外，尽管经过反复深入询问，受LJP影响的不同核心家庭之间未发现家族联系。两组之间的PlI和GI没有显著差异，而LJP组的BOP、PPD和PAL显著高于非LJP组。这些发现强烈表明环境因素对该病的病因有影响。
