SWISS-2DPAGE数据库：过去一年有哪些变化。

The SWISS-2DPAGE database: what has changed during the last year.

作者信息

Hoogland C, Sanchez J C, Tonella L, Bairoch A, Hochstrasser D F, Appel R D

机构信息

Swiss Institute of Bioinformatics, c/o Medical Informatics Division, Geneva University Hospital, 24 rue Micheli-du-Crest, 1211 Geneva 14, Switzerland.

出版信息

Nucleic Acids Res. 1999 Jan 1;27(1):289-91. doi: 10.1093/nar/27.1.289.

DOI:10.1093/nar/27.1.289

PMID:9847204

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC148159/

Abstract

SWISS-2DPAGE (http://www.expasy.ch/ch2d/) is an annotated two-dimensional polyacrylamide gel electrophoresis (2-D PAGE) database established in 1993. The current release contains 21 reference maps from human and mouse biological samples, as well as from Saccharomyces cerevisiae, Escherichia coli and Dictyostelium discoideum origin. These reference maps now have 2480 identified spots, corresponding to 528 separate protein entries in the database, in addition to virtual entries for each SWISS-PROT sequence. During the last year, the SWISS-2DPAGE has undergone major changes. Six new maps have been added, and new functions to access the data have been provided through the ExPASy server. Finally, an important change concerns the database funding source.

摘要

SWISS-2DPAGE（http://www.expasy.ch/ch2d/）是一个于1993年建立的注释二维聚丙烯酰胺凝胶电泳（2-D PAGE）数据库。当前版本包含来自人类和小鼠生物样本以及酿酒酵母、大肠杆菌和盘基网柄菌来源的21张参考图谱。这些参考图谱目前有2480个已识别的斑点，对应数据库中的528个独立蛋白质条目，此外还有每个SWISS-PROT序列的虚拟条目。在过去一年中，SWISS-2DPAGE经历了重大变化。新增了6张图谱，并通过ExPASy服务器提供了访问数据的新功能。最后，一个重要的变化涉及数据库的资金来源。