Banerjee-Basu S, Ferlanti E S, Ryan J F, Baxevanis A D
Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health,Building 49, Room 2C-76, Bethesda, MD 20892-4431, USA.
Nucleic Acids Res. 1999 Jan 1;27(1):336-7. doi: 10.1093/nar/27.1.336.
The Homeodomain Resource is a comprehensive collection of sequence, structure and genomic information on the homeodomain protein family. Available through the Resource are both full-length and domain-only sequence data, as well as X-ray and NMR structural data for proteins and protein-DNA complexes. Also available is information on human genetic diseases and disorders in which proteins from the homeodomain family play an important role; genomic information includes relevant gene symbols, cytogenetic map locations, and specific mutation data. Search engines are provided to allow users to easily query the component databases and assemble specialized data sets. The Homeodomain Resource is available through the World Wide Web at http://genome.nhgri.nih.gov/homeodomain
同源异型结构域资源库全面收集了同源异型结构域蛋白家族的序列、结构和基因组信息。通过该资源库可获取全长和仅结构域的序列数据,以及蛋白质和蛋白质 - DNA 复合物的 X 射线和核磁共振结构数据。此外,还提供了关于同源异型结构域家族蛋白起重要作用的人类遗传疾病和病症的信息;基因组信息包括相关基因符号、细胞遗传图谱位置和特定突变数据。提供了搜索引擎,以便用户轻松查询组件数据库并组装专门的数据集。可通过万维网访问同源异型结构域资源库,网址为 http://genome.nhgri.nih.gov/homeodomain