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西诺沙星对2968株临床分离细菌的体外抗菌活性。

In vitro antimicrobial activity of cinoxacin against 2,968 clinical bacterial isolates.

作者信息

Jones R N, Fuchs P C

出版信息

Antimicrob Agents Chemother. 1976 Jul;10(1):146-9. doi: 10.1128/AAC.10.1.146.

DOI:10.1128/AAC.10.1.146
PMID:984747
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC429704/
Abstract

Cinoxacin demonstrated effective in vitro antimicrobial activity against the Enterobacteriaceae, but negligible activity against Pseudomonas aeruginosa and gram-positive cocci. The activity of cinoxacin was slightly greater than that of nalidixic acid.

摘要

西诺沙星对肠杆菌科细菌显示出有效的体外抗菌活性，但对铜绿假单胞菌和革兰氏阳性球菌的活性可忽略不计。西诺沙星的活性略高于萘啶酸。

相似文献

1
In vitro antimicrobial activity of cinoxacin against 2,968 clinical bacterial isolates.西诺沙星对2968株临床分离细菌的体外抗菌活性。
Antimicrob Agents Chemother. 1976 Jul;10(1):146-9. doi: 10.1128/AAC.10.1.146.
2
Studies on cinoxacin. 1. In vitro activity of cinoxacin, as compared to nalidixic acid, against urinary tract pathogens.西诺沙星的研究。1. 西诺沙星与萘啶酸相比，对尿路病原体的体外活性。
J Antimicrob Chemother. 1977 Sep;3(5):411-6. doi: 10.1093/jac/3.5.411.
3
Antibacterial activity of cinoxacin in vitro.西诺沙星的体外抗菌活性。
Antimicrob Agents Chemother. 1975 May;7(5):688-92. doi: 10.1128/AAC.7.5.688.
4
Cinoxacin: in vitro antibacterial studies of a new synthetic organic acid.西诺沙星：一种新型合成有机酸的体外抗菌研究
Antimicrob Agents Chemother. 1975 Feb;7(2):159-63. doi: 10.1128/AAC.7.2.159.
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In vitro activity of cinoxacin, an organic acid antibacterial.环丙沙星（一种有机酸抗菌剂）的体外活性
Antimicrob Agents Chemother. 1975 Mar;7(3):370-3. doi: 10.1128/AAC.7.3.370.
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In vitro synergistic activity of some chinolinic compounds combined with beta-lactam antibiotics against gram-positive and gram-negative clinical isolates.某些喹啉类化合物与β-内酰胺类抗生素联合对革兰氏阳性和革兰氏阴性临床分离株的体外协同活性。
Chemotherapy. 1985;31(3):191-9. doi: 10.1159/000238335.
7
Comparative in vitro activity of norfloxacin (MK-0366) and ten other oral antimicrobial agents against urinary bacterial isolates.诺氟沙星（MK-0366）与其他十种口服抗菌药物对尿细菌分离株的体外活性比较
Antimicrob Agents Chemother. 1982 May;21(5):848-51. doi: 10.1128/AAC.21.5.848.
8
In vitro susceptibility of urinary isolates of Escherichia coli to cinoxacin.大肠杆菌尿液分离株对西诺沙星的体外敏感性
J Antimicrob Chemother. 1979 Jul;5(4):413-8. doi: 10.1093/jac/5.4.413.
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Comparative in vitro studies of cinoxacin, nalidixic acid, and oxolinic acid.西诺沙星、萘啶酸和恶喹酸的体外比较研究。
Antimicrob Agents Chemother. 1976 Dec;10(6):918-20. doi: 10.1128/AAC.10.6.918.
10
In vitro activity of norfloxacin in synthetic media and human urine compared to that of cinnoxacin, nalidixic acid and pipemidic acid.与西诺沙星、萘啶酸和吡哌酸相比，诺氟沙星在合成培养基和人尿中的体外活性。
Methods Find Exp Clin Pharmacol. 1983 Dec;5(10):731-4.

引用本文的文献

1
In vitro activity of ciprofloxacin, a new carboxyquinoline antimicrobial agent.新型羧基喹啉抗菌剂环丙沙星的体外活性
Antimicrob Agents Chemother. 1984 Mar;25(3):331-5. doi: 10.1128/AAC.25.3.331.
2
Comparative pharmacokinetic profiles of cinoxacin and pipemidic acid in humans.西诺沙星和吡哌酸在人体中的比较药代动力学概况。
Eur J Drug Metab Pharmacokinet. 1983 Jul-Sep;8(3):251-9. doi: 10.1007/BF03188755.
3
Cinoxacin. A review of its pharmacological properties and therapeutic efficacy in the treatment of urinary tract infections.西诺沙星。其药理学特性及治疗尿路感染疗效的综述。
Drugs. 1983 Jun;25(6):544-69. doi: 10.2165/00003495-198325060-00002.
4
Ciprofloxacin in the treatment of urinary tract infections caused by Pseudomonas aeruginosa and multiresistant bacteria.
Eur J Clin Microbiol. 1986 Apr;5(2):255-7. doi: 10.1007/BF02014004.
5
Pharmacology of cinoxacin in humans.西诺沙星在人体中的药理学。
Antimicrob Agents Chemother. 1979 Feb;15(2):165-70. doi: 10.1128/AAC.15.2.165.

本文引用的文献

1
Compound 64716, a new synthetic antibacterial agent.化合物64716，一种新型合成抗菌剂。
Antimicrob Agents Chemother. 1973 Oct;4(4):415-20. doi: 10.1128/AAC.4.4.415.
2
Cinoxacin: effectiveness against experimental pyelonephritis in rats.西诺沙星：对大鼠实验性肾盂肾炎的疗效。
Antimicrob Agents Chemother. 1974 Oct;6(4):432-6. doi: 10.1128/AAC.6.4.432.
3
In vitro activity of cinoxacin, an organic acid antibacterial.环丙沙星（一种有机酸抗菌剂）的体外活性
Antimicrob Agents Chemother. 1975 Mar;7(3):370-3. doi: 10.1128/AAC.7.3.370.
4
Antibacterial activity of cinoxacin in vitro.西诺沙星的体外抗菌活性。
Antimicrob Agents Chemother. 1975 May;7(5):688-92. doi: 10.1128/AAC.7.5.688.
5
Cinoxacin: in vitro antibacterial studies of a new synthetic organic acid.西诺沙星：一种新型合成有机酸的体外抗菌研究
Antimicrob Agents Chemother. 1975 Feb;7(2):159-63. doi: 10.1128/AAC.7.2.159.