庆大霉素对病毒、衣原体和立克次氏体病原体在小鼠和鸡胚中生长的影响。
Effect of gentamicin on growth of viral, chlamydial, and rickettsial agents in mice and embryonated eggs.
作者信息
White L A, Hall H E, Tzianabos T, Chappell W A
出版信息
Antimicrob Agents Chemother. 1976 Aug;10(2):344-6. doi: 10.1128/AAC.10.2.344.
Abstract
Gentamicin, at concentrations up to 500 mug/ml, showed no effect on the replication, yield, or infectivity of seven viruses or on the agents of psittacosis and meningopneumonitis when grown in mice or embryonated eggs. At the 500 mug/ml level, lymphogranuloma venereum cultures had a slight reduction in infectivity. Rickettsia akari demonstrated susceptibility at the 5 mug/ml level, whereas R. rickettsii, R. mooseri, and R. canada grown in embryonated eggs were susceptible in varying degrees to gentamicin at or above the 50 mug/ml concentration.
摘要
庆大霉素在浓度高达500微克/毫升时，对七种病毒的复制、产量或感染性以及对在小鼠或鸡胚中培养的鹦鹉热和脑膜肺炎病原体均无影响。在500微克/毫升水平时，性病性淋巴肉芽肿培养物的感染性略有降低。五日热立克次体在5微克/毫升水平表现出敏感性，而在鸡胚中培养的立氏立克次体、莫氏立克次体和加拿大立克次体在50微克/毫升及以上浓度时对庆大霉素有不同程度的敏感性。
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