• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

庆大霉素对病毒、衣原体和立克次氏体病原体在小鼠和鸡胚中生长的影响。

Effect of gentamicin on growth of viral, chlamydial, and rickettsial agents in mice and embryonated eggs.

作者信息

White L A, Hall H E, Tzianabos T, Chappell W A

出版信息

Antimicrob Agents Chemother. 1976 Aug;10(2):344-6. doi: 10.1128/AAC.10.2.344.

DOI:10.1128/AAC.10.2.344
PMID:984775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC429745/
Abstract

Gentamicin, at concentrations up to 500 mug/ml, showed no effect on the replication, yield, or infectivity of seven viruses or on the agents of psittacosis and meningopneumonitis when grown in mice or embryonated eggs. At the 500 mug/ml level, lymphogranuloma venereum cultures had a slight reduction in infectivity. Rickettsia akari demonstrated susceptibility at the 5 mug/ml level, whereas R. rickettsii, R. mooseri, and R. canada grown in embryonated eggs were susceptible in varying degrees to gentamicin at or above the 50 mug/ml concentration.

摘要

庆大霉素在浓度高达500微克/毫升时,对七种病毒的复制、产量或感染性以及对在小鼠或鸡胚中培养的鹦鹉热和脑膜肺炎病原体均无影响。在500微克/毫升水平时,性病性淋巴肉芽肿培养物的感染性略有降低。五日热立克次体在5微克/毫升水平表现出敏感性,而在鸡胚中培养的立氏立克次体、莫氏立克次体和加拿大立克次体在50微克/毫升及以上浓度时对庆大霉素有不同程度的敏感性。

相似文献

1
Effect of gentamicin on growth of viral, chlamydial, and rickettsial agents in mice and embryonated eggs.庆大霉素对病毒、衣原体和立克次氏体病原体在小鼠和鸡胚中生长的影响。
Antimicrob Agents Chemother. 1976 Aug;10(2):344-6. doi: 10.1128/AAC.10.2.344.
2
Studies on the chemotherapy of viruses in the psittacosis-lymphogranuloma venereum group; effect of certain chemotherapeutic agents on the growth of psittacosis virus (6BC strain) in tissues cultures and eggs.鹦鹉热-性病性淋巴肉芽肿组病毒化疗研究;某些化疗药物对鹦鹉热病毒(6BC株)在组织培养物和鸡胚中生长的影响。
J Immunol. 1946 Jun;53:151-6.
3
Susceptibility of Rickettsia conorii and R. rickettsii to pefloxacin, in vitro and in ovo.康氏立克次体和立氏立克次体对培氟沙星的体外及卵内敏感性
J Antimicrob Chemother. 1987 Mar;19(3):303-5. doi: 10.1093/jac/19.3.303.
4
Use of gentamicin in the isolation of subgroup A Chlamydia.庆大霉素在分离A群衣原体中的应用。
Antimicrob Agents Chemother. 1973 Jun;3(6):698-702. doi: 10.1128/AAC.3.6.698.
5
Effect of aureomycin on viruses of the psittacosis-LGV group in embryonated eggs and mice.金霉素对鸡胚和小鼠中鹦鹉热-淋巴肉芽肿性病原体组病毒的作用。
Proc Soc Exp Biol Med. 1951 Jan;76(1):79-83. doi: 10.3181/00379727-76-18393.
6
THE ANTIGENIC RELATIONSHIP OF THE VIRUSES OF MENINGOPNEUMONITIS AND LYMPHOGRANULOMA VENEREUM.脑膜炎和淋巴肉芽肿病毒的抗原关系。
J Exp Med. 1942 Jan 1;75(1):21-33. doi: 10.1084/jem.75.1.21.
7
The effects of x-rays and beta rays (tritium) on the growth of Rickettsia mooseri and Rickettsia akari in embrvonate eggs.X射线和β射线(氚)对鸡胚卵中莫氏立克次体和小蛛立克次体生长的影响。
J Exp Med. 1960 Jun 1;111(6):841-9. doi: 10.1084/jem.111.6.841.
8
Metabolism of Rickettsia typhi and Rickettsia akari in irradiated L cells.鼠型斑疹伤寒立克次体和小蛛立克次体在经辐射的L细胞中的代谢
Infect Immun. 1972 Jul;6(1):50-7. doi: 10.1128/iai.6.1.50-57.1972.
9
[Observations on extracellular rickettsias (Rickettsia mooseri and R. quintana) and experimental modification of their properties].[关于细胞外立克次氏体(莫氏立克次氏体和五日热立克次氏体)及其特性的实验性改变的观察]
Z Tropenmed Parasitol. 1971 Dec;22(4):405-30.
10
Studies of the rickettsial plaque assay technique.立克次氏体蚀斑测定技术的研究
Infect Immun. 1972 May;5(5):715-22. doi: 10.1128/iai.5.5.715-722.1972.

引用本文的文献

1
Sensitization of intracellular Salmonella enterica serovar Typhimurium to aminoglycosides in vitro and in vivo by a host-targeted antimicrobial agent.一种宿主靶向抗菌剂在体外和体内使细胞内肠炎沙门氏菌鼠伤寒血清型对氨基糖苷类药物敏感化。
Antimicrob Agents Chemother. 2014 Dec;58(12):7375-82. doi: 10.1128/AAC.03778-14. Epub 2014 Sep 29.
2
Use of aminoglycosides in treatment of infections due to intracellular bacteria.氨基糖苷类药物在治疗细胞内细菌感染中的应用。
Antimicrob Agents Chemother. 2001 Nov;45(11):2977-86. doi: 10.1128/AAC.45.11.2977-2986.2001.
3
Antimicrobial therapy of rickettsial diseases.立克次体病的抗菌治疗。
Antimicrob Agents Chemother. 1991 Dec;35(12):2457-62. doi: 10.1128/AAC.35.12.2457.

本文引用的文献

1
The influence of certain salts, amino acids, sugars, and proteins on the stability of rickettsiae.某些盐类、氨基酸、糖类及蛋白质对立克次氏体稳定性的影响。
J Bacteriol. 1950 Apr;59(4):509-22. doi: 10.1128/jb.59.4.509-522.1950.
2
Antibiotic resistance in Mycoplasma isolates from tissue cultures.来自组织培养物的支原体分离株中的抗生素耐药性
Appl Microbiol. 1967 Jul;15(4):970. doi: 10.1128/am.15.4.970-.1967.
3
Antibacterial activity of gentamicin sulfate in tissue culture.硫酸庆大霉素在组织培养中的抗菌活性。
Appl Microbiol. 1970 Dec;20(6):989-90. doi: 10.1128/am.20.6.989-990.1970.
4
Standardized viral hemagglutination and hemagglutination-inhibition tests. II. Description and statistical evaluation.标准化病毒血凝及血凝抑制试验。II. 描述与统计学评估。
Appl Microbiol. 1969 Nov;18(5):824-33. doi: 10.1128/am.18.5.824-833.1969.
5
Gentamicin: in vitro studies.庆大霉素:体外研究
J Infect Dis. 1969 Apr-May;119(4):361-3. doi: 10.1093/infdis/119.4-5.361.
6
Use of gentamicin in the isolation of subgroup A Chlamydia.庆大霉素在分离A群衣原体中的应用。
Antimicrob Agents Chemother. 1973 Jun;3(6):698-702. doi: 10.1128/AAC.3.6.698.
7
Evaluation of gentamicin for use in virology and tissue culture.庆大霉素在病毒学和组织培养中的应用评估。
Appl Microbiol. 1972 Mar;23(3):565-70. doi: 10.1128/am.23.3.565-570.1972.
8
Recent microbiological studies with gentamicin.近期关于庆大霉素的微生物学研究。
J Infect Dis. 1969 Apr-May;119(4):355-60. doi: 10.1093/infdis/119.4-5.355.