Thomas M C, Jeffery G M
University of Otago, Dunedin, New Zealand.
Clin Oncol (R Coll Radiol). 1998;10(5):322-3. doi: 10.1016/s0936-6555(98)80087-3.
Sister Joseph's nodule is traditionally regarded as a sign of poor prognosis in untreatable malignancy. We describe a patient with a metastatic umbilical nodule in non-Hodgkin's lymphoma who had a good outcome. The possible mechanisms of tumour spread to the umbilicus and reasons for its rarity in lymphoma are discussed. The need for histological confirmation to exclude treatable disease is emphasized.
传统上认为，约瑟夫氏结节是不可治疗的恶性肿瘤预后不良的标志。我们描述了一名非霍奇金淋巴瘤患者出现转移性脐结节，但预后良好。本文讨论了肿瘤扩散至脐部的可能机制及其在淋巴瘤中罕见的原因。强调了通过组织学检查以排除可治疗疾病的必要性。
