冠心病调节慢性应激与代谢综合征之间的关系。
Coronary heart disease moderates the relationship of chronic stress with the metabolic syndrome.
作者信息
Vitaliano P P, Scanlan J M, Siegler I C, McCormick W C, Knopp R H
机构信息
Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle 98195, USA.
出版信息
Health Psychol. 1998 Nov;17(6):520-9. doi: 10.1037//0278-6133.17.6.520.
Metabolic syndrome levels (MSLs) were compared in caregivers (CGs) of spouses with Alzheimer's disease who had diagnoses of coronary heart disease (CHD; n = 27) with non CGs with CHD diagnoses (n = 18), and CGs (n = 44) to non CGs (n = 52) free of CHD. MSLs were greater for CGs than non CGs, but only in persons with CHD (CHD, B for CG status = -.41; non CHD, B = .12; p < .05) at study entry (Time 1 = T1) and CHD, B = -.32; non CHD, B = .14; p < .05) 15-18 months later (Time 2 = T2). In the CHD group, MSLs were associated with poorer health habits at T1 (r = .39, p < .01), uplifts (r = -.37, p < .01) at T2, and CG status (p < .05) at T1 and T2. Relationships of CG status and MSLs declined in the presence of poor health habits at T1 and uplifts at T2. Poorer health habits and fewer uplifts may be associated with elevated MSLs in CGs with CHD.
对患有阿尔茨海默病且被诊断患有冠心病（CHD；n = 27）的配偶的照料者（CGs）与被诊断患有冠心病的非照料者（n = 18），以及无冠心病的照料者（n = 44）与非照料者（n = 52）的代谢综合征水平（MSLs）进行了比较。在研究开始时（时间1 = T1），照料者的MSLs高于非照料者，但仅在患有冠心病的人群中如此（冠心病组，照料者状态的B值 = -0.41；非冠心病组，B值 = 0.12；p < 0.05），15 - 18个月后（时间2 = T2），冠心病组，B值 = -0.32；非冠心病组，B值 = 0.14；p < 0.05）。在冠心病组中，MSLs与T1时较差的健康习惯相关（r = 0.39，p < 0.01），与T2时的改善情况相关（r = -0.37，p < 0.01），以及与T1和T2时的照料者状态相关（p < 0.05）。在T1时存在较差的健康习惯以及T2时出现改善情况时，照料者状态与MSLs之间的关系减弱。较差的健康习惯和较少的改善情况可能与患有冠心病的照料者的MSLs升高有关。
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