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澳大利亚中部原住民儿童在8月龄及以后接种麻疹疫苗的有效性。

Measles vaccine effectiveness in central Australian aboriginal children vaccinated at or after eight months of age.

作者信息

Patel M, Lush D

机构信息

National Centre for Epidemiology and Population Health, Australian National University, Australian Capital Territory.

出版信息

Aust N Z J Public Health. 1998 Oct;22(6):729-30. doi: 10.1111/j.1467-842x.1998.tb01479.x.

DOI:10.1111/j.1467-842x.1998.tb01479.x
PMID:9848973
Abstract

An outbreak of measles in central Australia in 1994 provided the first opportunity to evaluate the effectiveness of the measles vaccine given to Aboriginal children at nine months of age since 1984. Children eligible for the study that was conducted in one community in the region were aged between nine months and 10 years. Eight of the 109 eligible children developed measles. The only unvaccinated child also developed measles. Vaccination failures occurred in 7.8% (6/77) of children vaccinated between eight and 11 months of age and in 3.2% (1/31) vaccinated after 11 months of age. Overall vaccine effectiveness was 93.5%. The level of vaccine uptake in central Australia is high and the last region-wide outbreak before 1994 occurred in 1981-82. If the age of vaccination against measles is to be determined by the average age of infection; the age of vaccination should now be raised to 12 months of age; this is the age at which Aboriginal children in all other states and all children in Australia are vaccinated.

摘要

1994年澳大利亚中部地区爆发的麻疹疫情,为评估自1984年起给原住民儿童在9个月大时接种麻疹疫苗的效果提供了首次机会。该地区一个社区开展的这项研究的 eligible儿童年龄在9个月至10岁之间。109名 eligible儿童中有8名患上了麻疹。唯一未接种疫苗的儿童也患上了麻疹。在8至11个月大时接种疫苗的儿童中,7.8%(6/77)出现了接种失败;在11个月大之后接种疫苗的儿童中,3.2%(1/31)出现了接种失败。总体疫苗有效性为93.5%。澳大利亚中部地区的疫苗接种率很高,1994年之前上一次全地区范围的疫情爆发发生在1981 - 1982年。如果麻疹疫苗接种年龄要由平均感染年龄来决定;那么现在疫苗接种年龄应提高到12个月;这是澳大利亚所有其他州的原住民儿童以及澳大利亚所有儿童接种疫苗的年龄。 (注:原文中“eligible”未翻译,因为不清楚其确切含义,需结合更多背景信息准确翻译,这里保留原文以待进一步明确)

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