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拟果蝇一个高突变株系的特征分析。

Characterization of a hypermutable strain of Drosophila simulans.

作者信息

Loreto E L, Zaha A, Nichols C, Pollock J A, Valente V L

机构信息

Departamento de Biologia, Universidade Federal de Santa Maria, RS, Brazil.

出版信息

Cell Mol Life Sci. 1998 Nov;54(11):1283-90. doi: 10.1007/s000180050254.

Abstract

A hypermutable strain of Drosophila simulans that originated from a single spontaneous mutant male was characterized. Seven different mutations were isolated from roughly 100 generations of offspring. The genetic analysis of the viable mutants showed two mutations on the X chromosome, one in the lozenge locus and the other in the ruby gene. The autosomic mutations characterized were a dpp-heldout-like, a blistered-like and a homoeotic dominant mutant with an antenna-to-leg transformation and ectopic eyes that we called Zoinho-napata.

摘要

对源自单个自发突变雄性果蝇的一个高变异性品系进行了表征。从大约100代后代中分离出了7种不同的突变。对存活突变体的遗传分析表明,在X染色体上有两个突变,一个在菱形基因座,另一个在红宝石基因中。所表征的常染色体突变有一个类似dpp-阻抑的突变、一个类似水泡的突变以及一个具有触角到腿的转变和异位眼的同源异型显性突变体,我们将其称为佐伊尼奥-纳帕塔。

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