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低眼压性青光眼患者的血小板功能、血液凝固性和纤维蛋白溶解

Platelet function, blood coagulability, and fibrinolysis in patients with low tension glaucoma.

作者信息

Joist J H, Lichtenfeld P, Mandell A I, Kolker A E

出版信息

Arch Ophthalmol. 1976 Nov;94(11):1893-5. doi: 10.1001/archopht.1976.03910040603002.

DOI:10.1001/archopht.1976.03910040603002
PMID:985164
Abstract

Platelet function in vitro and in vivo and certain measurements of blood coagulability and fibrinolysis were examined in 12 patients with low tension glaucoma and the results were compared with those obtained in 12 normal subjects matched for age, race, and sex. The data obtained seem to indicate that patients with low tension glaucoma cannot be readily distinguished from individuals of similar age and sex not afflicted with this disorder by measuring these variables. Thus, a "hypercoagulable state," ie, a thrombotic tendency, does not appear to be of major importance in the pathogenesis of this disorder.

摘要

对12例低眼压性青光眼患者的体外和体内血小板功能以及某些血液凝固性和纤维蛋白溶解指标进行了检测,并将结果与12名年龄、种族和性别相匹配的正常受试者的结果进行了比较。所获得的数据似乎表明,通过测量这些变量,低眼压性青光眼患者与未患该疾病的年龄和性别相似的个体难以轻易区分。因此,“高凝状态”,即血栓形成倾向,在该疾病的发病机制中似乎并不重要。

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Arch Ophthalmol. 1976 Nov;94(11):1893-5. doi: 10.1001/archopht.1976.03910040603002.
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引用本文的文献

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Association between coagulation function and patients with primary angle closure glaucoma: a 5-year retrospective case-control study.凝血功能与原发性闭角型青光眼患者的相关性:一项 5 年回顾性病例对照研究。
BMJ Open. 2017 Nov 4;7(11):e016719. doi: 10.1136/bmjopen-2017-016719.
2
Plasma vascular endothelial growth factor, soluble VEGF receptor FLT-1, and von Willebrand factor in glaucoma.青光眼患者血浆血管内皮生长因子、可溶性血管内皮生长因子受体FLT-1及血管性血友病因子水平
Br J Ophthalmol. 2002 Nov;86(11):1299-302. doi: 10.1136/bjo.86.11.1299.
3
Circulating platelet aggregates in glaucoma.
Int Ophthalmol. 1998;22(3):151-4. doi: 10.1023/a:1006279606494.
4
Normal tension glaucoma--a practical approach.正常眼压性青光眼——一种实用方法
Br J Ophthalmol. 1998 Jul;82(7):835-40. doi: 10.1136/bjo.82.7.835.
5
Systemic factors in patients with low-tension glaucoma.低眼压性青光眼患者的全身因素。
Br J Ophthalmol. 1981 Jan;65(1):56-62. doi: 10.1136/bjo.65.1.56.
6
Platelet aggregation and glaucoma.
Doc Ophthalmol. 1985 Nov 15;61(2):167-73. doi: 10.1007/BF00170723.
7
Blood and plasma viscosity measurements in patients with glaucoma.青光眼患者的血液和血浆粘度测量
Br J Ophthalmol. 1985 Oct;69(10):765-70. doi: 10.1136/bjo.69.10.765.
8
Results of a filtering procedure in low tension glaucoma.
Int Ophthalmol. 1989 Jan;13(1-2):131-8. doi: 10.1007/BF02028653.
9
Circulating lipoprotein and blood glucose levels in association with low-tension and chronic simple glaucoma.循环脂蛋白和血糖水平与低眼压性和慢性单纯性青光眼的关系
Br J Ophthalmol. 1977 Oct;61(10):641-5. doi: 10.1136/bjo.61.10.641.