Egger S F
Landesaugenklinik Salzburg.
Wien Med Wochenschr. 1997;147(12-13):295-7.
Disposable soft contact lenses (DSCLs) have been marketed as a safer alternative to conventional soft lenses. Extended-wear DSCLs are designed for one or two weeks of continuous use before disposal. Those for daily wear are designed for use as conventional daily wear soft lenses, with daily removal and storage for 2 to 4 weeks before disposal. Beside minor complications, such as corneal abrasion, giant papillary conjunctivitis and toxic epithelial reactions to contact lens solutions, the most serious complication occurring in contact lens users is ulcerative keratitis. Several case-control studies performed over the last years, demonstrated that disposable contact lenses were associated with a 14-fold excess risk of ulcerative keratitis compared with that for patients wearing conventional daily-wear soft contact lenses and a 13-fold excess risk compared with that for wearers of rigid gas permeable contact lenses. However, the major risk factor for corneal ulceration in contact lens wearers is overnight lens wear of 1 to 3 nights. It was estimated that 49 to 74% of cases of contact lens associated ulcerative keratitis could be prevented by eliminating overnight wear.
一次性软性隐形眼镜（DSCLs）已作为传统软性隐形眼镜的更安全替代品投放市场。长戴型DSCLs设计为在丢弃前可连续使用一至两周。日戴型则设计为像传统日戴软性隐形眼镜一样使用，每天摘下并保存2至4周后丢弃。除了轻微并发症，如角膜擦伤、巨乳头性结膜炎以及对隐形眼镜护理液的毒性上皮反应外，隐形眼镜使用者中出现的最严重并发症是溃疡性角膜炎。过去几年进行的几项病例对照研究表明，与佩戴传统日戴软性隐形眼镜的患者相比，一次性隐形眼镜导致溃疡性角膜炎的风险高出14倍，与佩戴硬性透气性隐形眼镜者相比则高出13倍。然而，隐形眼镜佩戴者角膜溃疡的主要风险因素是连续1至3晚过夜佩戴。据估计，通过消除过夜佩戴，49%至74%的隐形眼镜相关溃疡性角膜炎病例可得到预防。
