Bussolotto M, Ceccon A, Sergi G, Giantin V, Benincà P, Enzi G
Department of Internal Medicine, Division of Geriatrics, University of Padova, Italy.
Gerontology. 1999 Jan-Feb;45(1):39-43. doi: 10.1159/000022053.
In the literature there are several body impedance analysis (BIA) prediction equations generally determined in younger populations and their accuracy in the elderly has not been adequately confirmed.
We verified the reliability of the BIA method in a body composition study in the elderly.
To assess the accuracy of bioelectrical impedance analysis we compared this method with dual photon absorptiometry (DPA), assumed as a gold standard; body composition was predicted by seven BIA prediction equations in 24 healthy elderly individuals.
The best equation in fat-free mass (FFM) estimation is the RJL System formula (published by Segal in 1988); nevertheless, the wide range of the error in FFM estimating may limit its clinical application. The FFM hydration variability seems to be the principal variable which explains the error in FFM estimation by BIA prediction equations.
These findings indicate that the use of BIA equations is not interchangeable, when FFM is calculated in an elderly population, and more validation studies are necessary in this age group to evaluate the clinical application of this method.
文献中有多个身体阻抗分析(BIA)预测方程,这些方程通常是在较年轻人群中确定的,其在老年人中的准确性尚未得到充分证实。
我们在一项针对老年人的身体成分研究中验证了BIA方法的可靠性。
为评估生物电阻抗分析的准确性,我们将该方法与被视为金标准的双能光子吸收法(DPA)进行了比较;通过7个BIA预测方程对24名健康老年人的身体成分进行了预测。
在去脂体重(FFM)估计方面最佳的方程是RJL系统公式(由西格尔于1988年发表);然而,FFM估计中误差范围较宽可能会限制其临床应用。FFM水合作用变异性似乎是解释BIA预测方程在FFM估计中产生误差的主要变量。
这些发现表明,在老年人群中计算FFM时,使用BIA方程并非可以相互替换,并且在该年龄组中需要更多的验证研究来评估该方法的临床应用。