在农场使用DNA疫苗。

Out on the farm with DNA vaccines.

作者信息

Beard C W, Mason P W

机构信息

Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, NY 11944, USA.

出版信息

Nat Biotechnol. 1998 Dec;16(13):1325-8. doi: 10.1038/4298.

DOI:10.1038/4298

PMID:9853612

Abstract

DNA vaccination is a rapidly developing technology that offers new approaches for the prevention of disease. This technology may permit the production of new vaccines against diseases that have no current vaccine, as well as allowing the development of improved vaccines to replace existing products. We describe how DNA vaccination is being developed for use in commercial animal production, with an emphasis on viral diseases, and discuss the existing hurdles to its development and use.

摘要

DNA疫苗接种是一项快速发展的技术，为疾病预防提供了新方法。这项技术或许能够生产针对目前尚无疫苗的疾病的新型疫苗，同时也有助于研发改良疫苗以取代现有产品。我们描述了DNA疫苗接种技术在商业动物生产中的应用进展，重点介绍了其在病毒性疾病方面的应用，并讨论了该技术发展和应用过程中存在的障碍。