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双相障碍患者综合心理健康与药物滥用治疗综述。

Review of integrated mental health and substance abuse treatment for patients with dual disorders.

作者信息

Drake R E, Mercer-McFadden C, Mueser K T, McHugo G J, Bond G R

机构信息

Dartmouth Medical School, Lebanon, NH, USA.

出版信息

Schizophr Bull. 1998;24(4):589-608. doi: 10.1093/oxfordjournals.schbul.a033351.

Abstract

Patients with severe mental disorders such as schizophrenia and co-occurring substance use disorders traditionally received treatments for their two disorders from two different sets of clinicians in parallel treatment systems. Dissatisfaction with this clinical tradition led to the development of integrated treatment models in which the same clinicians or teams of clinicians provide substance abuse treatment and mental health treatment in a coordinated fashion. We reviewed 36 research studies on the effectiveness of integrated treatment for dually diagnosed patients. Studies of adding dual-disorders groups to traditional services, studies of intensive integrated treatments in controlled settings, and studies of demonstration projects have thus far yielded disappointing results. On the other hand, 10 recent studies of comprehensive, integrated outpatient treatment programs provide encouraging evidence of the programs' potential to engage dually diagnosed patients in services and to help them reduce substance abuse and attain remission. Outcomes related to hospital use, psychiatric symptoms, and other domains are less consistent. Several program features appear to be associated with effectiveness: assertive outreach, case management, and a longitudinal, stage-wise, motivational approach to substance abuse treatment. Given the magnitude and severity of the problem of dual disorders, more controlled research on integrated treatment is needed.

摘要

患有精神分裂症等严重精神障碍且同时患有物质使用障碍的患者,传统上是在并行治疗系统中由两组不同的临床医生分别对其两种疾病进行治疗。对这种临床传统的不满促使了综合治疗模式的发展,即由同一临床医生或临床医生团队以协调的方式提供物质滥用治疗和心理健康治疗。我们回顾了36项关于双诊断患者综合治疗效果的研究。到目前为止,在传统服务中增加双障碍组的研究、在受控环境中的强化综合治疗研究以及示范项目研究都取得了令人失望的结果。另一方面,最近对全面的综合门诊治疗项目进行的10项研究提供了令人鼓舞的证据,证明这些项目有潜力让双诊断患者接受服务,并帮助他们减少物质滥用并实现缓解。与住院使用、精神症状和其他领域相关的结果则不太一致。几个项目特征似乎与治疗效果相关:积极外展、病例管理以及对物质滥用治疗采用纵向、分阶段、激励性的方法。鉴于双障碍问题的规模和严重性,需要对综合治疗进行更多的对照研究。

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