Clinique Médicale II, Centre Marc-Sankalé, Fann-Dakar, Sénégal.
Sante. 1998 Sep-Oct;8(5):342-6.
Diabetes mellitus is becoming more common in African cities, where it may affect up to 7% of the hospital population. It particularly affects poor male patients and 73 to 80% of those affected have non insulin-dependent diabetes. The frequency of non-obese, poorly cetogenic patients is high in Sub-Saharan Africa. This may be due to malnutrition, with a deficit either in protein or in calories. Such malnutrition is a major public health problem affecting children in Sudanese and Sahelian areas and may interact with environmental and genetic factors. In equatorial environments, the toxic effects of alcohol abuse on the pancreas are simply another environmental factor, reducing the endocrine function of the pancreas. These observations are important because: 1) diabetes mellitus has a severe social impact in this area and 2) nutrition has a general effect on the pathogenesis of diabetes mellitus.
糖尿病在非洲城市正变得越来越普遍，在这些城市中，糖尿病患者可能占医院收治人群的7%。糖尿病尤其影响贫困男性患者，且73%至80%的患者患的是非胰岛素依赖型糖尿病。在撒哈拉以南非洲，非肥胖、生酮能力差的患者比例很高。这可能是由于营养不良，蛋白质或热量不足。这种营养不良是影响苏丹和萨赫勒地区儿童的一个主要公共卫生问题，并且可能与环境和遗传因素相互作用。在赤道地区，酗酒对胰腺的毒性作用只是另一个环境因素，会降低胰腺的内分泌功能。这些观察结果很重要，原因如下：1）糖尿病在该地区具有严重的社会影响；2）营养对糖尿病的发病机制具有普遍影响。
