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The pharmacoeconomic impact of antimicrobial therapy for peptic ulcer disease in a large urban jail.大城市监狱中消化性溃疡疾病抗菌治疗的药物经济学影响。
J Urban Health. 1998 Dec;75(4):896-902. doi: 10.1007/BF02344518.
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Treatment of Helicobacter pylori reduces the rate of rebleeding in peptic ulcer disease.幽门螺杆菌的治疗可降低消化性溃疡疾病的再出血率。
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本文引用的文献

1
Helicobacter pylori: consensus reached: peptic ulcer is on the way to becoming an historic disease.幽门螺杆菌：已达成共识：消化性溃疡正逐渐成为一种历史性疾病。
Am J Gastroenterol. 1994 Aug;89(8):1137-9.
2
NIH Consensus Conference. Helicobacter pylori in peptic ulcer disease. NIH Consensus Development Panel on Helicobacter pylori in Peptic Ulcer Disease.美国国立卫生研究院共识会议。幽门螺杆菌与消化性溃疡病。美国国立卫生研究院消化性溃疡病幽门螺杆菌共识发展小组。
JAMA. 1994 Jul 6;272(1):65-9.
3
Helicobacter pylori eradication in patients with peptic ulcer disease: clinical consequences and financial implications.
Q J Med. 1994 May;87(5):283-90.
4
Duodenal ulcer healing by eradication of Helicobacter pylori without anti-acid treatment: randomised controlled trial.通过根除幽门螺杆菌实现十二指肠溃疡愈合而无需抗酸治疗：随机对照试验
Lancet. 1994 Feb 26;343(8896):508-10. doi: 10.1016/s0140-6736(94)91460-5.
5
Antibacterial treatment of gastric ulcers associated with Helicobacter pylori.幽门螺杆菌相关性胃溃疡的抗菌治疗
N Engl J Med. 1995 Jan 19;332(3):139-42. doi: 10.1056/NEJM199501193320302.
6
The treatment of Helicobacter pylori infection in the management of peptic ulcer disease.消化性溃疡疾病管理中幽门螺杆菌感染的治疗
N Engl J Med. 1995 Oct 12;333(15):984-91. doi: 10.1056/NEJM199510123331508.
7
Alternative management strategies for patients with suspected peptic ulcer disease.疑似消化性溃疡疾病患者的替代管理策略。
Ann Intern Med. 1995 Aug 15;123(4):260-8. doi: 10.7326/0003-4819-123-4-199508150-00003.
8
Endoscopy in the evaluation of dyspepsia. Health and Public Policy Committee, American College of Physicians.消化不良评估中的内镜检查。美国医师协会健康与公共政策委员会
Ann Intern Med. 1985 Feb;102(2):266-9.
9
Effect of treatment of Helicobacter pylori infection on the long-term recurrence of gastric or duodenal ulcer. A randomized, controlled study.幽门螺杆菌感染治疗对胃或十二指肠溃疡长期复发的影响。一项随机对照研究。
Ann Intern Med. 1992 May 1;116(9):705-8. doi: 10.7326/0003-4819-116-9-705.

大城市监狱中消化性溃疡疾病抗菌治疗的药物经济学影响。

The pharmacoeconomic impact of antimicrobial therapy for peptic ulcer disease in a large urban jail.

作者信息

Shuter J, Fletcher D D, Simone V J, Bellin E Y

机构信息

Montefiore Rikers Island Health Services, USA.

出版信息

J Urban Health. 1998 Dec;75(4):896-902. doi: 10.1007/BF02344518.

DOI:10.1007/BF02344518
PMID:9854250
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3456001/
Abstract

PURPOSE

To determine the pharmacoeconomic impact of antimicrobial treatment of peptic ulcer disease (PUD) in a large urban jail.

PATIENTS AND METHODS

Retrospective comparison of PUD-related pharmacy and laboratory expenditures over a 2-year period before and after the institution of a PUD treatment protocol with the priority of Helicobacter pylori eradication for inmates in Rikers Island Correctional Facility.

RESULTS

After the protocol was adopted, total pharmacy-related and laboratory-related expenses for PUD care decreased by 40.2%, and expenditures for ranitidine declined by 52.2%. There was an increase in spending for antimicrobial agents and H. pylori antibody testing, but this was insignificant compared to the savings generated by decreased ranitidine usage. Annual savings in our facility as a result of this intervention were $123,449.

CONCLUSIONS

Modern therapeutic strategies for PUD aimed at eradicating H. pylori can result in significant savings in the institutional setting; these savings are largely attributable to the decreased usage of histamine-2 receptor antagonists.

摘要

目的

确定在一家大型城市监狱中，消化性溃疡疾病（PUD）抗菌治疗的药物经济学影响。

患者与方法

对雷克岛惩教所实施以根除幽门螺杆菌为优先的PUD治疗方案前后两年期间与PUD相关的药房和实验室支出进行回顾性比较。

结果

采用该方案后，PUD护理的药房相关和实验室相关总费用下降了40.2%，雷尼替丁支出下降了52.2%。抗菌药物和幽门螺杆菌抗体检测的费用有所增加，但与雷尼替丁使用量减少所产生的节省相比，这微不足道。由于这一干预措施，我们机构每年节省123,449美元。

结论

旨在根除幽门螺杆菌的PUD现代治疗策略可在机构环境中带来显著节省；这些节省主要归因于组胺-2受体拮抗剂使用量的减少。