大城市监狱中消化性溃疡疾病抗菌治疗的药物经济学影响。
The pharmacoeconomic impact of antimicrobial therapy for peptic ulcer disease in a large urban jail.
作者信息
Shuter J, Fletcher D D, Simone V J, Bellin E Y
机构信息
Montefiore Rikers Island Health Services, USA.
出版信息
J Urban Health. 1998 Dec;75(4):896-902. doi: 10.1007/BF02344518.
PURPOSE
To determine the pharmacoeconomic impact of antimicrobial treatment of peptic ulcer disease (PUD) in a large urban jail.
PATIENTS AND METHODS
Retrospective comparison of PUD-related pharmacy and laboratory expenditures over a 2-year period before and after the institution of a PUD treatment protocol with the priority of Helicobacter pylori eradication for inmates in Rikers Island Correctional Facility.
RESULTS
After the protocol was adopted, total pharmacy-related and laboratory-related expenses for PUD care decreased by 40.2%, and expenditures for ranitidine declined by 52.2%. There was an increase in spending for antimicrobial agents and H. pylori antibody testing, but this was insignificant compared to the savings generated by decreased ranitidine usage. Annual savings in our facility as a result of this intervention were $123,449.
CONCLUSIONS
Modern therapeutic strategies for PUD aimed at eradicating H. pylori can result in significant savings in the institutional setting; these savings are largely attributable to the decreased usage of histamine-2 receptor antagonists.
目的
确定在一家大型城市监狱中，消化性溃疡疾病（PUD）抗菌治疗的药物经济学影响。
患者与方法
对雷克岛惩教所实施以根除幽门螺杆菌为优先的PUD治疗方案前后两年期间与PUD相关的药房和实验室支出进行回顾性比较。
结果
采用该方案后，PUD护理的药房相关和实验室相关总费用下降了40.2%，雷尼替丁支出下降了52.2%。抗菌药物和幽门螺杆菌抗体检测的费用有所增加，但与雷尼替丁使用量减少所产生的节省相比，这微不足道。由于这一干预措施，我们机构每年节省123,449美元。
结论
旨在根除幽门螺杆菌的PUD现代治疗策略可在机构环境中带来显著节省；这些节省主要归因于组胺-2受体拮抗剂使用量的减少。
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