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[γ-氨基丁酸能药物对运动功能减退状态下电解质平衡的影响]

[The effect of GABA-ergic agents on the electrolyte balance under hypokinesia].

作者信息

Akopian V P, Edigarova L V

机构信息

Mkhitara Geratsi Erevan State Medical University, Department of Pharmacology, Republic of Armenia.

出版信息

Eksp Klin Farmakol. 1998 Sep-Oct;61(5):62-4.

PMID:9854639
Abstract

The effect of hypokinesia on the blood electrolyte balance was studied. In restricted motor activity marked deviations of the type of hypokalemia and hypercalcemia were encountered, which could promote the development of various pathological processes, including disorder of central and regional hemodynamics. GABA and piracetam had no effect on the blood serum electrolyte content in the early periods of hypokinesia. In later periods of hypokinesia both drugs under examination corrected the disorders of blood electrolyte balance induced by prolonged restriction of motor activity.

摘要

研究了运动减退对血液电解质平衡的影响。在运动活动受限的情况下,出现了低钾血症和高钙血症类型的明显偏差,这可能促进包括中枢和局部血流动力学紊乱在内的各种病理过程的发展。在运动减退的早期,γ-氨基丁酸和吡拉西坦对血清电解质含量没有影响。在运动减退的后期,所研究的两种药物都纠正了因长期运动活动受限而引起的血液电解质平衡紊乱。

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