Eliava Sh Sh, Oganesian K G, Dausheva A A, Filatova Iu M, Zolotukhin S P, Belousova O B, Amcheslavskiĭ V G, Toma G I, Saribekian A S
Zh Vopr Neirokhir Im N N Burdenko. 1998 Jul-Sep(3):15-9.
Changes in intracranial pressure (ICP) and cerebral circulation were evaluated from Doppler transcranial ultrasound (DTU) in 29 patients with spontaneous aneurysmal hemorrhage in acute rupture. There is a tendency for the pulse wave amplitude (PWA) of ICP to increase concurrently with higher ICP values (r = 0.768, p < 0.01), the tendency being smoother in patients with severe diffuse spasm (r = 0.573, p < 0.01). There was also a linear correlation between the ICP values and the pulse index of blood flow velocity (r = 0.783, p < 0.01). Evidence is given for the possibility of indirect assessment of ICP from DTU data and for that of indirect evaluation of cerebral perfusion from ICP monitoring data. In the latter case, the authors used a ICP PWA ratio. The findings suggest that the decrease in PWA/ICP values by less than 0.2 during intracranial hypertension and severe diffuse arterial spasm corresponds to the reduction in cerebral blood filling beyond the critical values.
通过经颅多普勒超声（DTU）对29例急性破裂的自发性动脉瘤性出血患者的颅内压（ICP）和脑循环变化进行了评估。ICP的脉搏波振幅（PWA）有随着ICP值升高而同时增加的趋势（r = 0.768，p < 0.01），在严重弥漫性痉挛患者中这种趋势更明显（r = 0.573，p < 0.01）。ICP值与血流速度脉搏指数之间也存在线性相关性（r = 0.783，p < 0.01）。有证据表明可从DTU数据间接评估ICP，也可从ICP监测数据间接评估脑灌注。在后一种情况下，作者使用了ICP的PWA比值。研究结果表明，在颅内高压和严重弥漫性动脉痉挛期间，PWA/ICP值下降小于0.2对应于脑血容量减少超过临界值。
