Méndez E, Sabaté M, García-Baez P, Santana C, Rodríguez M
Department of Physiology, University of La Laguna, Tenerife, Spain.
J Neurol Neurosurg Psychiatry. 1998 Dec;65(6):921-3. doi: 10.1136/jnnp.65.6.921.
It has been suggested that a deficit in timing could be the cause of the sensory disturbances reported for Parkinson's disease. To test this hypothesis the temporal discrimination thresholds in four visual tasks were used to study 45 healthy young people, 14 healthy elderly people, and 17 patients with Parkinson's disease. In these tasks, subjects watched a computer controlled light emitting diode display and pushed a button when the visual event previously specified by the researcher was perceived. The time between successive images required to discriminate a visual detail was accurately quantified. In two of the four tasks, the time for visual processing of image sequences was longer in the elderly group than in the young group. No significant differences were found between patients with Parkinson's disease and their age matched controls for any of the four tasks. Present data show normal temporal discrimination and no slowing in the initial steps of visual processing in Parkinson's disease.
有人提出，时间感知缺陷可能是帕金森病所报告的感觉障碍的原因。为了验证这一假设，我们使用四项视觉任务中的时间辨别阈值，对45名健康年轻人、14名健康老年人和17名帕金森病患者进行了研究。在这些任务中，受试者观看计算机控制的发光二极管显示器，并在感知到研究人员先前指定的视觉事件时按下按钮。辨别视觉细节所需的连续图像之间的时间被精确量化。在四项任务中的两项中，老年组处理图像序列的视觉时间比年轻组长。在四项任务中的任何一项中，帕金森病患者与其年龄匹配的对照组之间均未发现显著差异。目前的数据表明，帕金森病患者的时间辨别正常，视觉处理的初始步骤没有减慢。
