Plenk H
Department for Bone and Biomaterials Research, Histological-Embryological Institute, University of Vienna, Austria.
J Biomed Mater Res. 1998 Winter;43(4):350-5. doi: 10.1002/(sici)1097-4636(199824)43:4<350::aid-jbm2>3.0.co;2-s.
In this overview, which is based on selected books and reviews, the microscopic appearances of prosthesis-bone interfaces resulting from clinically relevant implantation techniques are highlighted. The following techniques are distinguished to insert and attach prostheses in the recipient bone: impaction into bone, primary mechanical interlocking, cement fixation, bone ongrowth and secondary mechanical interlocking with bioinert materials, and enhanced bone ongrowth and bone bonding to bioactive materials. The resulting typical histomorphologies of orthopedic and dental prostheses-bone interfaces are described and illustrated from the author's studies employing light, fluorescence, and backscattered electron microscopy, and corresponding microradiographs of undecalcified ground sections of bone and implants. Special emphasis is given to the mineralization-demineralization kinetics of the interfacial bone matrix interacting with specific surface reactions of some implant materials. Consequently, the distinction between bioinert and bioactive prosthetic materials is critically analyzed.
在本综述中，基于所选书籍和评论，重点介绍了临床相关植入技术所导致的假体 - 骨界面的微观表现。以下是在受体骨中插入和附着假体的不同技术：冲击入骨、初次机械互锁、骨水泥固定、骨长入以及与生物惰性材料的二次机械互锁，还有增强的骨长入和与生物活性材料的骨结合。利用光学、荧光和背散射电子显微镜以及相应的骨和植入物未脱钙磨片的显微放射照片，描述并展示了作者研究中矫形和牙科假体 - 骨界面产生的典型组织形态。特别强调了与某些植入材料的特定表面反应相互作用的界面骨基质的矿化 - 脱矿动力学。因此，对生物惰性和生物活性假体材料之间的区别进行了批判性分析。
