Durupt S, Boibieux A, Ballet-Mechain M, Chaumentin G, Tremeau G, Roure C, Peyramond D
Service des Maladies infectieuses, Hôpital de la Croix Rousse, Lyon.
Presse Med. 1998 Nov 21;27(36):1839-41.
Propionibacterium acnes, a Gram positive microaerophilic bacteria is considered to have a low level of virulence. Nevertheless, it can be associated with infective endocarditis. We report 2 cases and a review of the literature.
The first man developed an acute prosthetic valve infective endocarditis and died. The second case was also a prosthetic valve infective endocarditis in a patient who developed infectious spondylitis.
P. acnes is an uncommon causal agent in infective endocarditis and appears to have a predilectio for prosthetic valves. A prior history of skin infection is rare. P. acnes grow quite slowly, often requiring 7 to 14 days for identification. All isolates of P. acnes from blood or valve do not necessarily mean contamination.
痤疮丙酸杆菌是一种革兰氏阳性微需氧菌，其毒力被认为较低。然而，它可与感染性心内膜炎相关。我们报告2例病例并对文献进行综述。
首例男性患者发生急性人工瓣膜感染性心内膜炎并死亡。第二例也是人工瓣膜感染性心内膜炎患者，该患者并发感染性脊柱炎。
痤疮丙酸杆菌是感染性心内膜炎中一种不常见的病原体，似乎对人工瓣膜有偏好。既往皮肤感染史罕见。痤疮丙酸杆菌生长相当缓慢，通常需要7至14天才能鉴定出来。从血液或瓣膜中分离出的所有痤疮丙酸杆菌菌株不一定意味着污染。
