Pan Sung-Ching, Wang Jann-Tay, Hsueh Po-Ren, Chang Shan-Chwen
Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7 Chung-Shan South Road, Taipei 100, Taiwan, ROC.
J Infect. 2005 Nov;51(4):e229-31. doi: 10.1016/j.jinf.2005.02.006.
Propionibacterium acnes, which usually considered as a contaminant, has been found to be an emerging pathogen in human diseases. We describe a case of prosthetic valve related endocarditis caused by P. acnes. Sequencing of the genetic coding of 16S ribosomal RNA was used to identify the pathogen and random amplified polymorphic DNA patterns further confirmed the persistent bacteraemia, which help to determine the diagnosis.
痤疮丙酸杆菌通常被认为是一种污染物，但现已发现它是人类疾病中一种新出现的病原体。我们描述了一例由痤疮丙酸杆菌引起的人工瓣膜相关心内膜炎病例。通过对16S核糖体RNA的遗传编码进行测序来鉴定病原体，随机扩增多态性DNA模式进一步证实了持续性菌血症，这有助于明确诊断。
