Seminara P, Lucá F, Gualdi G, Donato V, Accettura C, Peverini P, Franchi F
Department of Clinical Medicine, University of Rome La Sapienza, Italy.
Am J Med Sci. 1998 Dec;316(6):398-400. doi: 10.1097/00000441-199812000-00008.
The authors observed a long-lasting response to uninterrupted vinorelbine treatment in a 72-year-old patient with a stage IIIB unresectable non-small cell carcinoma. The progressive tumor mass reduction was assessed by computed tomographic scans over a 2-year period. In the literature, data of randomized trials confirm that the appeal of single-agent vinorelbine therapy in elderly patients is also good for the patient's quality of life during treatment.
作者观察到一名72岁的IIIB期不可切除非小细胞癌患者对持续的长春瑞滨治疗产生了持久反应。通过计算机断层扫描在2年期间评估肿瘤肿块的逐渐缩小情况。在文献中,随机试验的数据证实,单药长春瑞滨治疗对老年患者的吸引力也有利于患者治疗期间的生活质量。