Renal localization of 67Ga-citrate in renal amyloidosis: case reports.

In scans taken 72 hr after intravenous administration of 5 mCi of 67Ga-citrate, both kidneys were clearly visible in two cases of histologically proven renal amyloidosis. Neither patient had clinical manifestations or laboratory evidence of concurrent inflammatory disease or tumor involving the kidneys. Increased renal concentration of lysosomal organelles and increased affinity of 67Ga for amyloid material contained in the organelles could explain the renal uptake of 67Ga in amyloidosis.