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Envoplakin and periplakin are components of the paraneoplastic pemphigus antigen complex.

作者信息

Kiyokawa C, Ruhrberg C, Nie Z, Karashima T, Mori O, Nishikawa T, Green K J, Anhalt G J, DiColandrea T, Watt F M, Hashimoto T

出版信息

J Invest Dermatol. 1998 Dec;111(6):1236-8. doi: 10.1046/j.1523-1747.1998.00449.x.

DOI:10.1046/j.1523-1747.1998.00449.x
PMID:9856851
Abstract
摘要

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Envoplakin and periplakin are components of the paraneoplastic pemphigus antigen complex.桥粒斑蛋白和周斑蛋白是副肿瘤性天疱疮抗原复合物的组成成分。
J Invest Dermatol. 1998 Dec;111(6):1236-8. doi: 10.1046/j.1523-1747.1998.00449.x.
2
The members of the plakin family of proteins recognized by paraneoplastic pemphigus antibodies include periplakin.副肿瘤性天疱疮抗体识别的plakin家族蛋白质成员包括周膜蛋白。
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Envoplakin and periplakin, the paraneoplastic pemphigus antigens, are also recognized by pemphigus foliaceus autoantibodies.
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Paraneoplastic pemphigus sera react strongly with multiple epitopes on the various regions of envoplakin and periplakin, except for the c-terminal homologous domain of periplakin.副肿瘤性天疱疮血清与envoplakin和periplakin不同区域的多个表位发生强烈反应,但periplakin的C末端同源结构域除外。
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Envoplakin and periplakin are the paraneoplastic pemphigus antigens.桥粒斑蛋白和周斑蛋白是副肿瘤性天疱疮抗原。
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Epitopes in the linker subdomain region of envoplakin recognized by autoantibodies in paraneoplastic pemphigus patients.副肿瘤性天疱疮患者自身抗体识别的桥粒斑蛋白连接子亚结构域区域的表位
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Periplakin and envoplakin are target antigens in canine and human paraneoplastic pemphigus.桥粒斑蛋白和副粒斑蛋白是犬类和人类副肿瘤性天疱疮中的靶抗原。
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Development of ELISA for the specific determination of autoantibodies against envoplakin and periplakin in paraneoplastic pemphigus.开发针对副肿瘤性天疱疮中 envoplakin 和 periplakin 的自身抗体的 ELISA 检测方法。
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Autoantibodies from a patient with paraneoplastic pemphigus bind periplakin, a novel member of the plakin family.
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