Department of Dermatology and Allergology, Philipps University, 35043 Marburg, Germany.
First Dermatology Division, IDI-IRCCS, 00167 Rome, Italy.
Int J Mol Sci. 2020 Mar 21;21(6):2178. doi: 10.3390/ijms21062178.
Skin manifestations of systemic disease and malignancy are extremely polymorphous. Clinicians should be familiarized with paraneoplastic dermatoses in order to perform an early diagnosis of the underlying neoplasm. Lack of familiarity with cutaneous clues of internal malignancy may delay diagnosis and treatment of cancer. In this review, we described several paraneoplastic dermatoses and discussed extensively two paradigmatic ones, namely paraneoplastic pemphigus and paraneoplastic dermatomyositis.
系统性疾病和恶性肿瘤的皮肤表现极其多样。临床医生应熟悉副肿瘤性皮肤病,以便对潜在的肿瘤进行早期诊断。对皮肤恶性肿瘤线索缺乏熟悉可能会延迟癌症的诊断和治疗。在这篇综述中,我们描述了几种副肿瘤性皮肤病,并详细讨论了两种典型的皮肤病,即副肿瘤性天疱疮和副肿瘤性皮肌炎。