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成人会厌炎:多伦多医院的经验

Adult epiglottitis: the Toronto Hospital experience.

作者信息

Solomon P, Weisbrod M, Irish J C, Gullane P J

机构信息

Department of Otolaryngology/Head and Neck Program, Toronto Hospital, University of Toronto, Ontario.

出版信息

J Otolaryngol. 1998 Dec;27(6):332-6.

PMID:9857318
Abstract

OBJECTIVE

This study was conducted to gain insight into the diagnosis, treatment, and outcome measures in adult patients presenting with acute epiglottitis.

METHOD

A retrospective clinical study was conducted on fifty-seven consecutive adult patients presenting with acute epiglottitis over a 13-year period to The Toronto Hospital, University of Toronto. Demographic description of patient population, presenting symptoms and signs, investigations performed, treatment provided, and incidence of complications were described.

RESULTS

Soft-tissue lateral neck x-rays were abnormal in 88.1% of patients tested but had a 12% false-negative rate. Indirect, direct, or flexible laryngoscopy were the most accurate investigations to establish diagnosis and were not associated with any complications. Four of 45 patients (8.9%) had positive blood cultures for Haemophilus influenzae, with the remainder demonstrating no growth, while 22% of patients (8/36) grew possible pathogenic organisms on throat culture. A rapid clinical course (< 12 hr), evidence of tachycardia, or positive pharyngeal or blood cultures were factors that selected for a group of patients requiring formal airway intervention.

CONCLUSIONS

Adult epiglottitis is different from its paediatric counterpart in that organism identification is less common, the clinical course is more gradual, there is less seasonal variation, airway compromise is more uncommon, and conservative airway management can be contemplated in the selected patient. Adult epiglottitis can be managed safely with a selective approach to airway management with airway intervention for any patient with signs of critical airway compromise.

摘要

目的

本研究旨在深入了解成年急性会厌炎患者的诊断、治疗及预后指标。

方法

对多伦多大学多伦多医院13年间连续收治的57例成年急性会厌炎患者进行回顾性临床研究。描述了患者群体的人口统计学特征、症状和体征、所做检查、治疗措施及并发症发生率。

结果

88.1%接受检查的患者颈部软组织侧位X线片异常,但假阴性率为12%。间接喉镜、直接喉镜或纤维喉镜检查是确诊的最准确方法,且未引发任何并发症。45例患者中有4例(8.9%)血培养流感嗜血杆菌阳性,其余无细菌生长,而22%的患者(8/36)咽拭子培养出可能的致病微生物。临床病程进展迅速(<12小时)、心动过速、咽拭子或血培养阳性是一组需要进行正规气道干预患者的相关因素。

结论

成人会厌炎与儿童会厌炎不同,在于病原菌鉴定不常见、临床病程较缓慢、季节变化较小、气道梗阻较少见,且对部分患者可考虑保守气道管理。对于有严重气道梗阻迹象的任何患者,采用选择性气道管理方法并进行气道干预,可安全地治疗成人会厌炎。

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