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腹腔镜抗反流手术:尼森、尼森-罗塞蒂和图佩特胃底折叠术的比较研究。法国腹腔镜外科学会

Laparoscopic antireflux surgery: comparative study of Nissen, Nissen-Rossetti, and Toupet fundoplication. Société Française de Chirurgie Laparoscopique.

作者信息

Pessaux P, Arnaud J P, Ghavami B, Flament J B, Trebuchet G, Meyer C, Huten N, Champault G

机构信息

Department of Visceral Surgery, Chu-Angers, 4 Rue Larrey, 49033 Angers Cedex 01, France.

出版信息

Surg Endosc. 2000 Nov;14(11):1024-7.

Abstract

BACKGROUND

The aim of this retrospective study was to compare the results of Nissen, Nissen-Rossetti, and Toupet laparoscopic fundoplication in terms of gastroesophageal reflux disease (GERD).

METHODS

From 1992 to 1996, 1,470 laparoscopic fundoplications were performed using one of three procedures: Nissen (n = 655), Nissen-Rossetti (n = 423), and Toupet (n = 392). Preoperative checkup included esophagogastroduodenoscopy in 1,437 patients (97. 7%), esophageal manometry in 934 patients (63.5%), and 24-h pH-metry in 799 patients (54.3%). The results were estimated at 1 month, 3 months, and 2 years. Patients unable to visit the hospital center were contacted by telephone.

RESULTS

The three groups were quite similar regarding demographic data such as age, gender, preoperative clinical symptoms, and duration of GERD. One death (0.07%) occurred. At 3 months, there were no differences among the three groups concerning conversion, morbidity, dysphagia, early reintervention, or postoperative length of stay. The length of surgery was more important in the Toupet procedure. In the Nissen group, there were fewer Visick grade I patients but more Visick grade III patients. At 2 years, the recurrence and reintervention rates were similar. The overall residual severe dysphagia rate was 0.35% (n = 5). In the Nissen group, there were fewer Visick grade I patients but more in Visick grade II patients. There was no difference in Visick grade III and IV among the groups. More than 90% of the patients were satisfied (Visick I + Visick II), with no significant difference among the three groups.

CONCLUSIONS

The results of this study do not differ significantly from the data reported in the literature, suggesting such surgical techniques are effective and well tolerated, and that both can be properly used in the treatment of GERD.

摘要

背景

这项回顾性研究的目的是比较尼森(Nissen)、尼森 - 罗塞蒂(Nissen-Rossetti)和图佩特(Toupet)腹腔镜胃底折叠术在治疗胃食管反流病(GERD)方面的效果。

方法

1992年至1996年期间,采用三种手术方法之一进行了1470例腹腔镜胃底折叠术:尼森术式(n = 655)、尼森 - 罗塞蒂术式(n = 423)和图佩特术式(n = 392)。术前检查包括1437例患者(97.7%)进行了食管胃十二指肠镜检查,934例患者(63.5%)进行了食管测压,799例患者(54.3%)进行了24小时pH值监测。在1个月、3个月和2年时评估结果。无法到医院中心就诊的患者通过电话联系。

结果

三组在年龄、性别、术前临床症状和GERD病程等人口统计学数据方面非常相似。发生了1例死亡(0.07%)。在3个月时,三组在中转开腹、发病率、吞咽困难、早期再次干预或术后住院时间方面没有差异。手术时间在图佩特术式中更长。在尼森组中,维西克(Visick)I级患者较少,但维西克III级患者较多。在2年时,复发率和再次干预率相似。总体残余严重吞咽困难率为0.35%(n = 5)。在尼森组中,维西克I级患者较少,但维西克II级患者较多。三组在维西克III级和IV级方面没有差异。超过90%的患者满意(维西克I + 维西克II),三组之间没有显著差异。

结论

本研究结果与文献报道的数据没有显著差异,表明此类手术技术有效且耐受性良好,两者均可适用于GERD的治疗。

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