Nowakowski A, Labaziewicz L, Skrzypek H
Katedra i Klinika Ortopedii, Akademia Medyczna w Poznaniu.
Chir Narzadow Ruchu Ortop Pol. 1998;63(4):317-20.
Authors present current knowledge about incidence and etiologic factors in idiopathic scoliosis (IS). Most data about incidence are based on screening examination in school children. Amount of patient with IS is related to the method of evaluation and experience of examiner. There is 1.9% to 3% cases in whole population if scoliosis is assumed as much as 10 degrees of Cobb angle (SRS). Etiology of IS is still in doubt despite of many investigations. There are many abnormalities in tissues but most of them probably secondary to this process. Etiology is multifactorial with dominance of inheritance. There are many genes responsible for occurrence of IS but genetic trait is still unknown.
作者介绍了有关特发性脊柱侧凸(IS)发病率和病因的当前知识。大多数关于发病率的数据基于对学童的筛查检查。IS患者的数量与评估方法和检查者的经验有关。如果将Cobb角(SRS)达到10度的脊柱侧凸视为脊柱侧凸,那么整个人口中的病例数为1.9%至3%。尽管进行了许多研究,但IS的病因仍存在疑问。组织中存在许多异常,但其中大多数可能是该过程的继发性结果。病因是多因素的,遗传因素占主导。有许多基因与IS的发生有关,但遗传特征仍然未知。