Romano J G, Babikian V L, Wijman C A, Hedges T R
Department of Neurology, University of Miami, School of Medicine, Florida, USA.
J Neuroophthalmol. 1998 Dec;18(4):237-41.
Retinal ischemia is often caused by emboli arising from the cardiac chambers or the common carotid artery bifurcation; the latter are often composed of cholesterol. However, in many patients no lesions are identified after evaluation of these sources of emboli. Two patients were observed who had retinal ischemia and emboli originating from aortic atheromatous plaques that were visualized by transesophageal echocardiography. Cardiac, carotid, and intracranial sources of emboli were excluded. The embolic nature of retinal ischemia was further corroborated by the presence of microembolic signals during transcranial Doppler insonation of the middle cerebral artery on the side ipsilateral to the symptomatic retina. In patients with Hollenhorst plaques the aortic arch can be a potential source of emboli. Transesophageal echocardiography should be considered in these patients when the initial evaluation does not identify a cardiac or carotid lesion.
视网膜缺血通常由源自心腔或颈总动脉分叉处的栓子引起;后者通常由胆固醇组成。然而,在许多患者中,对这些栓子来源进行评估后未发现病变。观察到两名患有视网膜缺血且栓子源自主动脉粥样斑块的患者,经食管超声心动图可显示这些斑块。已排除心脏、颈动脉和颅内的栓子来源。在症状性视网膜同侧的大脑中动脉经颅多普勒超声检查期间,微栓子信号的存在进一步证实了视网膜缺血的栓子性质。在患有霍伦霍斯特斑块的患者中,主动脉弓可能是栓子的潜在来源。当初始评估未发现心脏或颈动脉病变时,应考虑对这些患者进行经食管超声心动图检查。